Lolis EJ - Search Results

1

MIF intersubunit disulfide mutant antagonist supports activation of CD74 by endogenous MIF trimer at physiologic concentrations.

Fan C, Rajasekaran D, Syed MA, Leng L, Loria JP, Bhandari V, Bucala R, Lolis EJ. Fan C, et al. Among authors: lolis ej. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):10994-9. doi: 10.1073/pnas.1221817110. Epub 2013 Jun 17. Proc Natl Acad Sci U S A. 2013. PMID: 23776208 Free PMC article.

2

Crystal structure at 2.6-A resolution of human macrophage migration inhibitory factor.

Sun HW, Bernhagen J, Bucala R, Lolis E. Sun HW, et al. Proc Natl Acad Sci U S A. 1996 May 28;93(11):5191-6. doi: 10.1073/pnas.93.11.5191. Proc Natl Acad Sci U S A. 1996. PMID: 8643551 Free PMC article.

3

The subunit structure of human macrophage migration inhibitory factor: evidence for a trimer.

Sun HW, Swope M, Cinquina C, Bedarkar S, Bernhagen J, Bucala R, Lolis E. Sun HW, et al. Protein Eng. 1996 Aug;9(8):631-5. doi: 10.1093/protein/9.8.631. Protein Eng. 1996. PMID: 8875640

4

Crystal structure of macrophage migration inhibitory factor (MIF), a glucocorticoid-induced regulator of cytokine production, reveals a unique architecture.

Lolis E, Bucala R. Lolis E, et al. Proc Assoc Am Physicians. 1996 Nov;108(6):415-9. Proc Assoc Am Physicians. 1996. PMID: 8956364 Review.

5

Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1alpha, a potent ligand for the HIV-1 "fusin" coreceptor.

Dealwis C, Fernandez EJ, Thompson DA, Simon RJ, Siani MA, Lolis E. Dealwis C, et al. Among authors: lolis e. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6941-6. doi: 10.1073/pnas.95.12.6941. Proc Natl Acad Sci U S A. 1998. PMID: 9618518 Free PMC article.

6

Pro-1 of macrophage migration inhibitory factor functions as a catalytic base in the phenylpyruvate tautomerase activity.

Lubetsky JB, Swope M, Dealwis C, Blake P, Lolis E. Lubetsky JB, et al. Biochemistry. 1999 Jun 1;38(22):7346-54. doi: 10.1021/bi990306m. Biochemistry. 1999. PMID: 10353846

7

The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents.

Lubetsky JB, Dios A, Han J, Aljabari B, Ruzsicska B, Mitchell R, Lolis E, Al-Abed Y. Lubetsky JB, et al. J Biol Chem. 2002 Jul 12;277(28):24976-82. doi: 10.1074/jbc.M203220200. Epub 2002 May 7. J Biol Chem. 2002. PMID: 11997397 Free article.

8

Inhibition of MIF bioactivity by rational design of pharmacological inhibitors of MIF tautomerase activity.

Dios A, Mitchell RA, Aljabari B, Lubetsky J, O'Connor K, Liao H, Senter PD, Manogue KR, Lolis E, Metz C, Bucala R, Callaway DJ, Al-Abed Y. Dios A, et al. J Med Chem. 2002 Jun 6;45(12):2410-6. doi: 10.1021/jm010534q. J Med Chem. 2002. PMID: 12036350

9

Macrophage migration inhibitory factor.

Lolis E, Bucala R. Lolis E, et al. Expert Opin Ther Targets. 2003 Apr;7(2):153-64. doi: 10.1517/14728222.7.2.153. Expert Opin Ther Targets. 2003. PMID: 12667094 Review.

10

Therapeutic approaches to innate immunity: severe sepsis and septic shock.

Lolis E, Bucala R. Lolis E, et al. Nat Rev Drug Discov. 2003 Aug;2(8):635-45. doi: 10.1038/nrd1153. Nat Rev Drug Discov. 2003. PMID: 12904813 Review. No abstract available.

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