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Elevated lactoferrin is associated with moderate to severe Clostridium difficile disease, stool toxin, and 027 infection.
Eur J Clin Microbiol Infect Dis. 2013 Dec;32(12):1517-23. doi: 10.1007/s10096-013-1905-x. Epub 2013 Jun 18.
Eur J Clin Microbiol Infect Dis. 2013.
PMID: 23771554
Free PMC article.
Glutamate dehydrogenase is highly conserved among Clostridium difficile ribotypes.
Carman RJ, Wickham KN, Chen L, Lawrence AM, Boone JH, Wilkins TD, Kerkering TM, Lyerly DM.
Carman RJ, et al. Among authors: wickham kn.
J Clin Microbiol. 2012 Apr;50(4):1425-6. doi: 10.1128/JCM.05600-11. Epub 2012 Feb 1.
J Clin Microbiol. 2012.
PMID: 22301027
Free PMC article.
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Ribotype 027 Clostridium difficile infections with measurable stool toxin have increased lactoferrin and are associated with a higher mortality.
Boone JH, Archbald-Pannone LR, Wickham KN, Carman RJ, Guerrant RL, Franck CT, Lyerly DM.
Boone JH, et al. Among authors: wickham kn.
Eur J Clin Microbiol Infect Dis. 2014 Jun;33(6):1045-51. doi: 10.1007/s10096-013-2043-1. Epub 2014 Jan 22.
Eur J Clin Microbiol Infect Dis. 2014.
PMID: 24449345
Free PMC article.
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In vivo selection of rifamycin-resistant Clostridium difficile during rifaximin therapy.
Carman RJ, Boone JH, Grover H, Wickham KN, Chen L.
Carman RJ, et al. Among authors: wickham kn.
Antimicrob Agents Chemother. 2012 Nov;56(11):6019-20. doi: 10.1128/AAC.00974-12. Epub 2012 Aug 20.
Antimicrob Agents Chemother. 2012.
PMID: 22908175
Free PMC article.
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