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103 results

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SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4.
Tiek D, Wells CI, Schröder M, Song X, Alamillo-Ferrer C, Goenka A, Iglesia R, Lu M, Hu B, Kwarcinski F, Sintha P, de Silva C, Hossain MA, Picado A, Zuercher W, Zutshi R, Knapp S, Riggins RB, Cheng SY, Drewry DH. Tiek D, et al. Among authors: zuercher w. Curr Res Chem Biol. 2023;3:100045. doi: 10.1016/j.crchbi.2023.100045. Epub 2023 Sep 22. Curr Res Chem Biol. 2023. PMID: 38009092 Free PMC article.
Open Source Antibiotics: Simple Diarylimidazoles Are Potent against Methicillin-Resistant Staphylococcus aureus.
Klug DM, Tse EG, Silva DG, Cao Y, Charman SA, Chauhan J, Crighton E, Dichiara M, Drake C, Drewry D, da Silva Emery F, Ferrins L, Graves L, Hopkins E, Kresina TAC, Lorente-Macías Á, Perry B, Phipps R, Quiroga B, Quotadamo A, Sabatino GN, Sama A, Schätzlein A, Simpson QJ, Steele J, Shanu-Wilson J, Sjö P, Stapleton P, Swain CJ, Vaideanu A, Xie H, Zuercher W, Todd MH. Klug DM, et al. Among authors: zuercher w. ACS Infect Dis. 2023 Dec 8;9(12):2423-2435. doi: 10.1021/acsinfecdis.3c00286. Epub 2023 Nov 22. ACS Infect Dis. 2023. PMID: 37991879 Free PMC article.
Structure-activity relationship of dihydropyridines for rhabdomyosarcoma.
Chauhan S, Woods AD, Bharathy N, Lian X, Ricker CA, Mantz A, Zuercher WJ, Price LH, Morton MJ, Durrant E, Corbel SY, Sampath SC, Sampath SC, Joslin J, Keller C. Chauhan S, et al. Among authors: zuercher wj. Biochem Biophys Res Commun. 2023 Jul 30;667:138-145. doi: 10.1016/j.bbrc.2023.04.114. Epub 2023 May 6. Biochem Biophys Res Commun. 2023. PMID: 37224633
Identification of Inhibitors of the Schistosoma mansoni VKR2 Kinase Domain.
Mathavan I, Liu LJ, Robinson SW, El-Sakkary N, Elatico AJJ, Gomez D, Nellas R, Owens RJ, Zuercher W, Navratilova I, Caffrey CR, Beis K. Mathavan I, et al. Among authors: zuercher w. ACS Med Chem Lett. 2022 Oct 5;13(11):1715-1722. doi: 10.1021/acsmedchemlett.2c00248. eCollection 2022 Nov 10. ACS Med Chem Lett. 2022. PMID: 36385939 Free PMC article.
Multiparameter phenotypic screening for endogenous TFEB and TFE3 translocation identifies novel chemical series modulating lysosome function.
Carling PJ, Ryan BJ, McGuinness W, Kataria S, Humble SW, Milde S, Duce JA, Kapadia N, Zuercher WJ, Davis JB, Di Daniel E, Wade-Martins R. Carling PJ, et al. Among authors: zuercher wj. Autophagy. 2023 Feb;19(2):692-705. doi: 10.1080/15548627.2022.2095834. Epub 2022 Jul 25. Autophagy. 2023. PMID: 35786165 Free PMC article.
Temozolomide-induced guanine mutations create exploitable vulnerabilities of guanine-rich DNA and RNA regions in drug-resistant gliomas.
Tiek DM, Erdogdu B, Razaghi R, Jin L, Sadowski N, Alamillo-Ferrer C, Hogg JR, Haddad BR, Drewry DH, Wells CI, Pickett JE, Song X, Goenka A, Hu B, Goldlust SA, Zuercher WJ, Pertea M, Timp W, Cheng SY, Riggins RB. Tiek DM, et al. Among authors: zuercher wj. Sci Adv. 2022 Jun 24;8(25):eabn3471. doi: 10.1126/sciadv.abn3471. Epub 2022 Jun 22. Sci Adv. 2022. PMID: 35731869 Free PMC article.
103 results