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Altered methylation of IGF2 DMR0 is associated with neural tube defects.
Wu L, Wang L, Shangguan S, Chang S, Wang Z, Lu X, Zhang Q, Wang J, Zhao H, Wang F, Guo J, Niu B, Guo J, Zhang T. Wu L, et al. Among authors: chang s. Mol Cell Biochem. 2013 Aug;380(1-2):33-42. doi: 10.1007/s11010-013-1655-1. Epub 2013 May 21. Mol Cell Biochem. 2013. PMID: 23690138
DNA methylation aberrations rather than polymorphisms of FZD3 gene increase the risk of spina bifida in a high-risk region for neural tube defects.
Shangguan S, Wang L, Chang S, Lu X, Wang Z, Wu L, Wang J, Wang X, Guan Z, Bao Y, Zhao H, Zou J, Niu B, Zhang T. Shangguan S, et al. Among authors: chang s. Birth Defects Res A Clin Mol Teratol. 2015 Jan;103(1):37-44. doi: 10.1002/bdra.23285. Epub 2014 Aug 18. Birth Defects Res A Clin Mol Teratol. 2015. PMID: 25131656
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