Broyde S - Search Results

1

Free energy profiles of base flipping in intercalative polycyclic aromatic hydrocarbon-damaged DNA duplexes: energetic and structural relationships to nucleotide excision repair susceptibility.

Cai Y, Zheng H, Ding S, Kropachev K, Schwaid AG, Tang Y, Mu H, Wang S, Geacintov NE, Zhang Y, Broyde S. Cai Y, et al. Among authors: broyde s. Chem Res Toxicol. 2013 Jul 15;26(7):1115-25. doi: 10.1021/tx400156a. Epub 2013 Jul 2. Chem Res Toxicol. 2013. PMID: 23758590 Free PMC article.

2

Solution conformation of the major adduct between the carcinogen (+)-anti-benzo[a]pyrene diol epoxide and DNA.

Cosman M, de los Santos C, Fiala R, Hingerty BE, Singh SB, Ibanez V, Margulis LA, Live D, Geacintov NE, Broyde S, et al. Cosman M, et al. Among authors: broyde s. Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1914-8. doi: 10.1073/pnas.89.5.1914. Proc Natl Acad Sci U S A. 1992. PMID: 1311854 Free PMC article.

3

Influence of benzo[a]pyrene diol epoxide chirality on solution conformations of DNA covalent adducts: the (-)-trans-anti-[BP]G.C adduct structure and comparison with the (+)-trans-anti-[BP]G.C enantiomer.

de los Santos C, Cosman M, Hingerty BE, Ibanez V, Margulis LA, Geacintov NE, Broyde S, Patel DJ. de los Santos C, et al. Among authors: broyde s. Biochemistry. 1992 Jun 16;31(23):5245-52. doi: 10.1021/bi00138a002. Biochemistry. 1992. PMID: 1606148

4

Structures of the (+)- and (-)-trans-7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne adducts to guanine-N2 in a duplex dodecamer.

Singh SB, Hingerty BE, Singh UC, Greenberg JP, Geacintov NE, Broyde S. Singh SB, et al. Among authors: broyde s. Cancer Res. 1991 Jul 1;51(13):3482-92. Cancer Res. 1991. PMID: 1905197

5

Synthesis and conformation of a dinucleoside monophosphate modified by aniline.

Jacobson MD, Shapiro R, Underwood GR, Broyde S, Verna L, Hingerty BE. Jacobson MD, et al. Among authors: broyde s. Chem Res Toxicol. 1988 May-Jun;1(3):152-9. doi: 10.1021/tx00003a005. Chem Res Toxicol. 1988. PMID: 2979725

6

Structural alignments of (+)- and (-)-trans-anti-benzo[a]pyrene-dG adducts positioned at a DNA template-primer junction.

Cosman M, Hingerty BE, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Among authors: broyde s. Biochemistry. 1995 Nov 21;34(46):15334-50. doi: 10.1021/bi00046a043. Biochemistry. 1995. PMID: 7578150

7

Solution conformation of the N-(deoxyguanosin-8-yl)aminofluorene adduct opposite deoxyinosine and deoxyguanosine in DNA by NMR and computational characterization.

Abuaf P, Hingerty BE, Broyde S, Grunberger D. Abuaf P, et al. Among authors: broyde s. Chem Res Toxicol. 1995 Apr-May;8(3):369-78. doi: 10.1021/tx00045a008. Chem Res Toxicol. 1995. PMID: 7578923

8

Major and minor groove conformations of DNA trimers modified on guanine or adenine by 4-aminobiphenyl: adenine adducts favor the minor groove.

Shapiro R, Ellis S, Hingerty BE, Broyde S. Shapiro R, et al. Among authors: broyde s. Chem Res Toxicol. 1995 Jan-Feb;8(1):117-27. doi: 10.1021/tx00043a016. Chem Res Toxicol. 1995. PMID: 7703355

9

Solution conformation of the (-)-trans-anti-5-methylchrysene-dG adduct opposite dC in a DNA duplex: DNA bending associated with wedging of the methyl group of 5-methylchrysene to the 3'-side of the modification site.

Cosman M, Xu R, Hingerty BE, Amin S, Harvey RG, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Among authors: broyde s. Biochemistry. 1995 May 9;34(18):6247-60. doi: 10.1021/bi00018a029. Biochemistry. 1995. PMID: 7742330

10

Solution conformation of the (-)-trans-anti-benzo[c]phenanthrene-dA ([BPh]dA) adduct opposite dT in a DNA duplex: intercalation of the covalently attached benzo[c]phenanthrenyl ring to the 3'-side of the adduct site and comparison with the (+)-trans-anti-[BPh]dA opposite dT stereoisomer.

Cosman M, Laryea A, Fiala R, Hingerty BE, Amin S, Geacintov NE, Broyde S, Patel DJ. Cosman M, et al. Among authors: broyde s. Biochemistry. 1995 Jan 31;34(4):1295-307. doi: 10.1021/bi00004a024. Biochemistry. 1995. PMID: 7827077

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