Wittlin S - Search Results

1

UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells.

Brunner R, Ng CL, Aissaoui H, Akabas MH, Boss C, Brun R, Callaghan PS, Corminboeuf O, Fidock DA, Frame IJ, Heidmann B, Le Bihan A, Jenö P, Mattheis C, Moes S, Müller IB, Paguio M, Roepe PD, Siegrist R, Voss T, Welford RW, Wittlin S, Binkert C. Brunner R, et al. Among authors: wittlin s. J Biol Chem. 2013 Aug 2;288(31):22576-83. doi: 10.1074/jbc.M113.453159. Epub 2013 Jun 10. J Biol Chem. 2013. PMID: 23754276 Free PMC article.

2

Plasmodium vivax: in vitro susceptibility of blood stages to synthetic trioxolane compounds and the diamidine DB75.

Kocken CH, van der Wel A, Arbe-Barnes S, Brun R, Matile H, Scheurer C, Wittlin S, Thomas AW. Kocken CH, et al. Among authors: wittlin s. Exp Parasitol. 2006 Jul;113(3):197-200. doi: 10.1016/j.exppara.2005.12.016. Epub 2006 Feb 3. Exp Parasitol. 2006. PMID: 16458301

3

In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum.

Maerki S, Brun R, Charman SA, Dorn A, Matile H, Wittlin S. Maerki S, et al. Among authors: wittlin s. J Antimicrob Chemother. 2006 Jul;58(1):52-8. doi: 10.1093/jac/dkl209. Epub 2006 May 30. J Antimicrob Chemother. 2006. PMID: 16735432

4

Peroxide bond-dependent antiplasmodial specificity of artemisinin and OZ277 (RBx11160).

Kaiser M, Wittlin S, Nehrbass-Stuedli A, Dong Y, Wang X, Hemphill A, Matile H, Brun R, Vennerstrom JL. Kaiser M, et al. Among authors: wittlin s. Antimicrob Agents Chemother. 2007 Aug;51(8):2991-3. doi: 10.1128/AAC.00225-07. Epub 2007 Jun 11. Antimicrob Agents Chemother. 2007. PMID: 17562801 Free PMC article.

5

Synthesis and in vitro antiprotozoal activities of water-soluble, inexpensive 3,7-bis(dialkylamino)phenoxazin-5-ium derivatives.

Ge JF, Arai C, Kaiser M, Wittlin S, Brun R, Ihara M. Ge JF, et al. Among authors: wittlin s. J Med Chem. 2008 Jun 26;51(12):3654-8. doi: 10.1021/jm8003619. Epub 2008 May 14. J Med Chem. 2008. PMID: 18476684

6

Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline.

Sparatore A, Basilico N, Casagrande M, Parapini S, Taramelli D, Brun R, Wittlin S, Sparatore F. Sparatore A, et al. Among authors: wittlin s. Bioorg Med Chem Lett. 2008 Jul 1;18(13):3737-40. doi: 10.1016/j.bmcl.2008.05.042. Epub 2008 May 16. Bioorg Med Chem Lett. 2008. PMID: 18538567

7

In vitro assessment of the pharmacodynamic properties of DB75, piperaquine, OZ277 and OZ401 in cultures of Plasmodium falciparum.

Hofer S, Brun R, Maerki S, Matile H, Scheurer C, Wittlin S. Hofer S, et al. Among authors: wittlin s. J Antimicrob Chemother. 2008 Nov;62(5):1061-4. doi: 10.1093/jac/dkn315. Epub 2008 Jul 30. J Antimicrob Chemother. 2008. PMID: 18669520 Free article.

8

A new double-antibody sandwich ELISA targeting Plasmodium falciparum aldolase to evaluate anti-malarial drug sensitivity.

Tritten L, Matile H, Brun R, Wittlin S. Tritten L, et al. Among authors: wittlin s. Malar J. 2009 Oct 12;8:226. doi: 10.1186/1475-2875-8-226. Malar J. 2009. PMID: 19821995 Free PMC article.

9

The structure-activity relationship of the antimalarial ozonide arterolane (OZ277).

Dong Y, Wittlin S, Sriraghavan K, Chollet J, Charman SA, Charman WN, Scheurer C, Urwyler H, Santo Tomas J, Snyder C, Creek DJ, Morizzi J, Koltun M, Matile H, Wang X, Padmanilayam M, Tang Y, Dorn A, Brun R, Vennerstrom JL. Dong Y, et al. Among authors: wittlin s. J Med Chem. 2010 Jan 14;53(1):481-91. doi: 10.1021/jm901473s. J Med Chem. 2010. PMID: 19924861

10

Ancient Chinese methods are remarkably effective for the preparation of artemisinin-rich extracts of Qing Hao with potent antimalarial activity.

Wright CW, Linley PA, Brun R, Wittlin S, Hsu E. Wright CW, et al. Among authors: wittlin s. Molecules. 2010 Feb 4;15(2):804-12. doi: 10.3390/molecules15020804. Molecules. 2010. PMID: 20335947 Free PMC article.

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