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Optimized ACE2 decoys neutralize antibody-resistant SARS-CoV-2 variants through functional receptor mimicry and treat infection in vivo.
Torchia JA, Tavares AH, Carstensen LS, Chen DY, Huang J, Xiao T, Mukherjee S, Reeves PM, Tu H, Sluder AE, Chen B, Kotton DN, Bowen RA, Saeed M, Poznansky MC, Freeman GJ. Torchia JA, et al. Among authors: kotton dn. Sci Adv. 2022 Dec 9;8(49):eabq6527. doi: 10.1126/sciadv.abq6527. Epub 2022 Dec 7. Sci Adv. 2022. PMID: 36475798 Free PMC article.
EMC3 regulates trafficking and pulmonary toxicity of the SFTPCI73T mutation associated with interstitial lung disease.
Tang X, Wei W, Sun Y, Weaver TE, Nakayasu ES, Clair G, Snowball JM, Na CL, Apsley KS, Martin EP, Kotton DN, Alysandratos KD, Huo J, Molkentin JD, Gower WA, Lin X, Whitsett JA. Tang X, et al. Among authors: kotton dn. J Clin Invest. 2024 Oct 15;134(23):e173861. doi: 10.1172/JCI173861. J Clin Invest. 2024. PMID: 39405113 Free PMC article.
Deciphering Endothelial and Mesenchymal Organ Specification in Vascularized Lung and Intestinal Organoids.
Miao Y, Tan C, Pek NM, Yu Z, Iwasawa K, Kechele DO, Sundaram N, Pastrana-Gomez V, Kishimoto K, Yang MC, Jiang C, Tchieu J, Whitsett JA, McCracken KW, Rottier RJ, Kotton DN, Helmrath MA, Wells JM, Takebe T, Zorn AM, Chen YW, Guo M, Gu M. Miao Y, et al. Among authors: kotton dn. bioRxiv [Preprint]. 2024 Feb 7:2024.02.06.577460. doi: 10.1101/2024.02.06.577460. bioRxiv. 2024. PMID: 38370768 Free PMC article. Preprint.
Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis.
Leung A, Nah SK, Reid W, Ebata A, Koch CM, Monti S, Genereux JC, Wiseman RL, Wolozin B, Connors LH, Berk JL, Seldin DC, Mostoslavsky G, Kotton DN, Murphy GJ. Leung A, et al. Among authors: kotton dn. Stem Cell Reports. 2013 Oct 31;1(5):451-63. doi: 10.1016/j.stemcr.2013.10.003. eCollection 2013. Stem Cell Reports. 2013. PMID: 24286032 Free PMC article.
Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.
Wilson AA, Ying L, Liesa M, Segeritz CP, Mills JA, Shen SS, Jean J, Lonza GC, Liberti DC, Lang AH, Nazaire J, Gower AC, Müeller FJ, Mehta P, Ordóñez A, Lomas DA, Vallier L, Murphy GJ, Mostoslavsky G, Spira A, Shirihai OS, Ramirez MI, Gadue P, Kotton DN. Wilson AA, et al. Among authors: kotton dn. Stem Cell Reports. 2015 May 12;4(5):873-85. doi: 10.1016/j.stemcr.2015.02.021. Epub 2015 Apr 2. Stem Cell Reports. 2015. PMID: 25843048 Free PMC article.
Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells.
Kurmann AA, Serra M, Hawkins F, Rankin SA, Mori M, Astapova I, Ullas S, Lin S, Bilodeau M, Rossant J, Jean JC, Ikonomou L, Deterding RR, Shannon JM, Zorn AM, Hollenberg AN, Kotton DN. Kurmann AA, et al. Among authors: kotton dn. Cell Stem Cell. 2015 Nov 5;17(5):527-42. doi: 10.1016/j.stem.2015.09.004. Epub 2015 Oct 22. Cell Stem Cell. 2015. PMID: 26593959 Free PMC article.
Thyroid Progenitors Are Robustly Derived from Embryonic Stem Cells through Transient, Developmental Stage-Specific Overexpression of Nkx2-1.
Dame K, Cincotta S, Lang AH, Sanghrajka RM, Zhang L, Choi J, Kwok L, Wilson T, Kańduła MM, Monti S, Hollenberg AN, Mehta P, Kotton DN, Ikonomou L. Dame K, et al. Among authors: kotton dn. Stem Cell Reports. 2017 Feb 14;8(2):216-225. doi: 10.1016/j.stemcr.2016.12.024. Epub 2017 Feb 2. Stem Cell Reports. 2017. PMID: 28162994 Free PMC article.
170 results