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Simultaneous treatment with azelnidipine and olmesartan inhibits apoptosis of Hl-1 cardiac myocytes expressing E334k cMyBPC.
Bahrudin U, Ikeda N, Utami SB, Maharani N, Morikawa K, Li P, Sobirin MA, Hasegawa A, Sakata S, Endo R, Rifqi S, Shirayoshi Y, Yamamoto K, Ninomiya H, Hisatome I. Bahrudin U, et al. Among authors: shirayoshi y. Drug Res (Stuttg). 2013 Oct;63(10):515-20. doi: 10.1055/s-0033-1347188. Epub 2013 Jun 5. Drug Res (Stuttg). 2013. PMID: 23740383
Impairment of ubiquitin-proteasome system by E334K cMyBPC modifies channel proteins, leading to electrophysiological dysfunction.
Bahrudin U, Morikawa K, Takeuchi A, Kurata Y, Miake J, Mizuta E, Adachi K, Higaki K, Yamamoto Y, Shirayoshi Y, Yoshida A, Kato M, Yamamoto K, Nanba E, Morisaki H, Morisaki T, Matsuoka S, Ninomiya H, Hisatome I. Bahrudin U, et al. Among authors: shirayoshi y. J Mol Biol. 2011 Nov 4;413(4):857-78. doi: 10.1016/j.jmb.2011.09.006. Epub 2011 Sep 12. J Mol Biol. 2011. PMID: 21939669
Stabilization of Kv1.5 channel protein by bepridil through its action as a chemical chaperone.
Suzuki S, Kurata Y, Li P, Notsu T, Hasegawa A, Ikeda N, Kato M, Miake J, Sakata S, Shiota G, Yoshida A, Ninomiya H, Higaki K, Yamamoto K, Shirayoshi Y, Hisatome I. Suzuki S, et al. Among authors: shirayoshi y. Eur J Pharmacol. 2012 Dec 5;696(1-3):28-34. doi: 10.1016/j.ejphar.2012.09.025. Epub 2012 Sep 28. Eur J Pharmacol. 2012. PMID: 23026372
Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.
Iwai C, Li P, Kurata Y, Hoshikawa Y, Morikawa K, Maharani N, Higaki K, Sasano T, Notsu T, Ishido Y, Miake J, Yamamoto Y, Shirayoshi Y, Ninomiya H, Nakai A, Murata S, Yoshida A, Yamamoto K, Hiraoka M, Hisatome I. Iwai C, et al. Among authors: shirayoshi y. Cardiovasc Res. 2013 Dec 1;100(3):520-8. doi: 10.1093/cvr/cvt200. Epub 2013 Aug 20. Cardiovasc Res. 2013. PMID: 23963841
Instability of KCNE1-D85N that causes long QT syndrome: stabilization by verapamil.
Sakata S, Kurata Y, Li P, Notsu T, Morikawa K, Miake J, Higaki K, Yamamoto Y, Yoshida A, Shirayoshi Y, Yamamoto K, Horie M, Ninomiya H, Kanzaki S, Hisatome I. Sakata S, et al. Among authors: shirayoshi y. Pacing Clin Electrophysiol. 2014 Jul;37(7):853-63. doi: 10.1111/pace.12360. Epub 2014 Feb 5. Pacing Clin Electrophysiol. 2014. PMID: 24499369
Uric Acid-Induced Enhancements of Kv1.5 Protein Expression and Channel Activity via the Akt-HSF1-Hsp70 Pathway in HL-1 Atrial Myocytes.
Taufiq F, Maharani N, Li P, Kurata Y, Ikeda N, Kuwabara M, Otani N, Miake J, Hasegawa A, Tsuneto M, Shirayoshi Y, Ninomiya H, Saitoh T, Nakai A, Yamamoto K, Hisatome I. Taufiq F, et al. Among authors: shirayoshi y. Circ J. 2019 Mar 25;83(4):718-726. doi: 10.1253/circj.CJ-18-1088. Epub 2019 Feb 20. Circ J. 2019. PMID: 30787218 Free article.
Pretreatment with cilnidipine attenuates hypoxia/reoxygenation injury in HL-1 cardiomyocytes through enhanced NO production and action potential shortening.
Minato H, Hisatome I, Kurata Y, Notsu T, Nakasone N, Ninomiya H, Hamada T, Tomomori T, Okamura A, Miake J, Tsuneto M, Shirayoshi Y, Endo R, Otsuki A, Okada F, Inagaki Y. Minato H, et al. Among authors: shirayoshi y. Hypertens Res. 2020 May;43(5):380-388. doi: 10.1038/s41440-019-0391-7. Epub 2020 Jan 15. Hypertens Res. 2020. PMID: 31942044
100 results