Miskimins WK - Search Results

1

Improved clearance during treatment of HPV-positive head and neck cancer through mTOR inhibition.

Coppock JD, Wieking BG, Molinolo AA, Gutkind JS, Miskimins WK, Lee JH. Coppock JD, et al. Among authors: miskimins wk. Neoplasia. 2013 Jun;15(6):620-30. doi: 10.1593/neo.13432. Neoplasia. 2013. PMID: 23730210 Free PMC article.

2

mTOR inhibition as an adjuvant therapy in a metastatic model of HPV+ HNSCC.

Coppock JD, Vermeer PD, Vermeer DW, Lee KM, Miskimins WK, Spanos WC, Lee JH. Coppock JD, et al. Among authors: miskimins wk. Oncotarget. 2016 Apr 26;7(17):24228-41. doi: 10.18632/oncotarget.8286. Oncotarget. 2016. PMID: 27015118 Free PMC article.

3

Dichloroacetate enhances apoptotic cell death via oxidative damage and attenuates lactate production in metformin-treated breast cancer cells.

Haugrud AB, Zhuang Y, Coppock JD, Miskimins WK. Haugrud AB, et al. Among authors: miskimins wk. Breast Cancer Res Treat. 2014 Oct;147(3):539-50. doi: 10.1007/s10549-014-3128-y. Epub 2014 Sep 12. Breast Cancer Res Treat. 2014. PMID: 25212175 Free PMC article.

4

Phase II study of dichloroacetate, an inhibitor of pyruvate dehydrogenase, in combination with chemoradiotherapy for unresected, locally advanced head and neck squamous cell carcinoma.

Powell SF, Mazurczak M, Dib EG, Bleeker JS, Geeraerts LH, Tinguely M, Lohr MM, McGraw SC, Jensen AW, Ellison CA, Black LJ, Puumala SE, Reed VJ, Miskimins WK, Lee JH, Spanos WC. Powell SF, et al. Among authors: miskimins wk. Invest New Drugs. 2022 Jun;40(3):622-633. doi: 10.1007/s10637-022-01235-5. Epub 2022 Mar 21. Invest New Drugs. 2022. PMID: 35312941 Free PMC article. Clinical Trial.

5

Mechanisms by which low glucose enhances the cytotoxicity of metformin to cancer cells both in vitro and in vivo.

Zhuang Y, Chan DK, Haugrud AB, Miskimins WK. Zhuang Y, et al. Among authors: miskimins wk. PLoS One. 2014 Sep 25;9(9):e108444. doi: 10.1371/journal.pone.0108444. eCollection 2014. PLoS One. 2014. PMID: 25254953 Free PMC article.

6

Synergistic anti-cancer effect of phenformin and oxamate.

Miskimins WK, Ahn HJ, Kim JY, Ryu S, Jung YS, Choi JY. Miskimins WK, et al. PLoS One. 2014 Jan 21;9(1):e85576. doi: 10.1371/journal.pone.0085576. eCollection 2014. PLoS One. 2014. PMID: 24465604 Free PMC article.

7

Metformin induces both caspase-dependent and poly(ADP-ribose) polymerase-dependent cell death in breast cancer cells.

Zhuang Y, Miskimins WK. Zhuang Y, et al. Among authors: miskimins wk. Mol Cancer Res. 2011 May;9(5):603-15. doi: 10.1158/1541-7786.MCR-10-0343. Epub 2011 Mar 21. Mol Cancer Res. 2011. PMID: 21422199 Free PMC article.

8

β₂-Adrenergic receptor modulates mitochondrial metabolism and disease progression in recurrent/metastatic HPV(+) HNSCC.

Lucido CT, Callejas-Valera JL, Colbert PL, Vermeer DW, Miskimins WK, Spanos WC, Vermeer PD. Lucido CT, et al. Among authors: miskimins wk. Oncogenesis. 2018 Oct 8;7(10):81. doi: 10.1038/s41389-018-0090-2. Oncogenesis. 2018. PMID: 30297705 Free PMC article.

9

Metformin and phenethyl isothiocyanate combined treatment in vitro is cytotoxic to ovarian cancer cultures.

Chan DK, Miskimins WK. Chan DK, et al. Among authors: miskimins wk. J Ovarian Res. 2012 Jul 10;5(1):19. doi: 10.1186/1757-2215-5-19. J Ovarian Res. 2012. PMID: 22781119 Free PMC article.

10

Lactate induces PD-L1 in HRAS^G12V-positive oropharyngeal squamous cell carcinoma.

Verma AK, Messerli SM, Miskimins WK. Verma AK, et al. Among authors: miskimins wk. Oncotarget. 2020 Apr 28;11(17):1493-1504. doi: 10.18632/oncotarget.27348. eCollection 2020 Apr 28. Oncotarget. 2020. PMID: 32391119 Free PMC article.

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