Jaffer ZM - Search Results

1

Therapeutic potential of HSP90 inhibition for neurofibromatosis type 2.

Tanaka K, Eskin A, Chareyre F, Jessen WJ, Manent J, Niwa-Kawakita M, Chen R, White CH, Vitte J, Jaffer ZM, Nelson SF, Rubenstein AE, Giovannini M. Tanaka K, et al. Among authors: jaffer zm. Clin Cancer Res. 2013 Jul 15;19(14):3856-70. doi: 10.1158/1078-0432.CCR-12-3167. Epub 2013 May 28. Clin Cancer Res. 2013. PMID: 23714726 Free PMC article.

2

The novel Hsp90 inhibitor NXD30001 induces tumor regression in a genetically engineered mouse model of glioblastoma multiforme.

Zhu H, Woolfenden S, Bronson RT, Jaffer ZM, Barluenga S, Winssinger N, Rubenstein AE, Chen R, Charest A. Zhu H, et al. Among authors: jaffer zm. Mol Cancer Ther. 2010 Sep;9(9):2618-26. doi: 10.1158/1535-7163.MCT-10-0248. Epub 2010 Jul 19. Mol Cancer Ther. 2010. PMID: 20643786 Free PMC article.

3

A novel small molecule HSP90 inhibitor, NXD30001, differentially induces heat shock proteins in nervous tissue in culture and in vivo.

Cha JR, St Louis KJ, Tradewell ML, Gentil BJ, Minotti S, Jaffer ZM, Chen R, Rubenstein AE, Durham HD. Cha JR, et al. Among authors: jaffer zm. Cell Stress Chaperones. 2014 May;19(3):421-35. doi: 10.1007/s12192-013-0467-2. Epub 2013 Oct 3. Cell Stress Chaperones. 2014. PMID: 24092395 Free PMC article.

4

p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.

Chow HY, Jubb AM, Koch JN, Jaffer ZM, Stepanova D, Campbell DA, Duron SG, O'Farrell M, Cai KQ, Klein-Szanto AJ, Gutkind JS, Hoeflich KP, Chernoff J. Chow HY, et al. Among authors: jaffer zm. Cancer Res. 2012 Nov 15;72(22):5966-75. doi: 10.1158/0008-5472.CAN-12-2246. Epub 2012 Sep 14. Cancer Res. 2012. PMID: 22983922 Free PMC article.

5

p21-activated kinases: three more join the Pak.

Jaffer ZM, Chernoff J. Jaffer ZM, et al. Int J Biochem Cell Biol. 2002 Jul;34(7):713-7. doi: 10.1016/s1357-2725(01)00158-3. Int J Biochem Cell Biol. 2002. PMID: 11950587 Review.

6

Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors.

Beeser A, Jaffer ZM, Hofmann C, Chernoff J. Beeser A, et al. Among authors: jaffer zm. J Biol Chem. 2005 Nov 4;280(44):36609-15. doi: 10.1074/jbc.M502306200. Epub 2005 Aug 29. J Biol Chem. 2005. PMID: 16129686 Free article.

7

p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.

Cotteret S, Jaffer ZM, Beeser A, Chernoff J. Cotteret S, et al. Among authors: jaffer zm. Mol Cell Biol. 2003 Aug;23(16):5526-39. doi: 10.1128/MCB.23.16.5526-5539.2003. Mol Cell Biol. 2003. PMID: 12897128 Free PMC article.

8

Visinin-like protein-1 is a potent inhibitor of cell adhesion and migration in squamous carcinoma cells.

Gonzalez Guerrico AM, Jaffer ZM, Page RE, Braunewell KH, Chernoff J, Klein-Szanto AJ. Gonzalez Guerrico AM, et al. Among authors: jaffer zm. Oncogene. 2005 Mar 31;24(14):2307-16. doi: 10.1038/sj.onc.1208476. Oncogene. 2005. PMID: 15735716

9

The cross-Rho'ds of cell-cell adhesion.

Jaffer ZM, Chernoff J. Jaffer ZM, et al. J Biol Chem. 2004 Aug 20;279(34):35123-6. doi: 10.1074/jbc.R400010200. Epub 2004 May 7. J Biol Chem. 2004. PMID: 15133033 Free article. Review. No abstract available.

10

PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics.

Smith SD, Jaffer ZM, Chernoff J, Ridley AJ. Smith SD, et al. Among authors: jaffer zm. J Cell Sci. 2008 Nov 15;121(Pt 22):3729-36. doi: 10.1242/jcs.027680. Epub 2008 Oct 21. J Cell Sci. 2008. PMID: 18940914 Free PMC article.

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