Wang S - Search Results

1

Affinity and kinetic modulation of polyamide-DNA interactions by N-modification of the heterocycles.

Ramos JP, Babu B, Chavda S, Liu Y, Plaunt A, Ferguson A, Savagian M, Lee M, Tzou S, Lin S, Kiakos K, Wang S, Lee M, Hartley JA, Wilson WD. Ramos JP, et al. Among authors: wang s. Biopolymers. 2013 Aug;99(8):497-507. doi: 10.1002/bip.22205. Biopolymers. 2013. PMID: 23712486 Free PMC article.

2

Correlation of local effects of DNA sequence and position of β-alanine inserts with polyamide-DNA complex binding affinities and kinetics.

Wang S, Nanjunda R, Aston K, Bashkin JK, Wilson WD. Wang S, et al. Biochemistry. 2012 Dec 11;51(49):9796-806. doi: 10.1021/bi301327v. Epub 2012 Nov 28. Biochemistry. 2012. PMID: 23167504 Free PMC article.

3

Design, synthesis, and DNA binding characteristics of a group of orthogonally positioned diamino, N-formamido, pyrrole- and imidazole-containing polyamides.

Chavda S, Babu B, Patil P, Plaunt A, Ferguson A, Lee M, Tzou S, Sjoholm R, Rice T, Mackay H, Ramos J, Wang S, Lin S, Kiakos K, Wilson WD, Hartley JA, Lee M. Chavda S, et al. Among authors: wang s. Bioorg Med Chem. 2013 Jul 1;21(13):3907-18. doi: 10.1016/j.bmc.2013.04.001. Epub 2013 Apr 10. Bioorg Med Chem. 2013. PMID: 23647824

4

Conformational modulation of DNA by polyamide binding: structural effects of f-Im-Py-Im based derivatives on 5'-ACGCGT-3'.

Wang S, Chai Y, Babu B, Satam V, Lee M, David Wilson W. Wang S, et al. J Mol Recognit. 2013 Aug;26(8):331-40. doi: 10.1002/jmr.2273. J Mol Recognit. 2013. PMID: 23784989 Free PMC article.

5

Modulation of DNA-polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics.

Wang S, Aston K, Koeller KJ, Harris GD Jr, Rath NP, Bashkin JK, Wilson WD. Wang S, et al. Org Biomol Chem. 2014 Oct 14;12(38):7523-36. doi: 10.1039/c4ob01456a. Org Biomol Chem. 2014. PMID: 25141096 Free PMC article.

6

AzaHx, a novel fluorescent, DNA minor groove and G·C recognition element: Synthesis and DNA binding properties of a p-anisyl-4-aza-benzimidazole-pyrrole-imidazole (azaHx-PI) polyamide.

Satam V, Babu B, Patil P, Brien KA, Olson K, Savagian M, Lee M, Mepham A, Jobe LB, Bingham JP, Pett L, Wang S, Ferrara M, Bruce CD, Wilson WD, Lee M, Hartley JA, Kiakos K. Satam V, et al. Among authors: wang s. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3681-5. doi: 10.1016/j.bmcl.2015.06.055. Epub 2015 Jun 19. Bioorg Med Chem Lett. 2015. PMID: 26122210

7

Minor groove to major groove, an unusual DNA sequence-dependent change in bend directionality by a distamycin dimer.

Wang S, Munde M, Wang S, Wilson WD. Wang S, et al. Biochemistry. 2011 Sep 6;50(35):7674-83. doi: 10.1021/bi201010g. Epub 2011 Aug 10. Biochemistry. 2011. PMID: 21800847 Free PMC article.

8

Molecular basis for sequence-dependent induced DNA bending.

Rettig M, Germann MW, Wang S, Wilson WD. Rettig M, et al. Among authors: wang s. Chembiochem. 2013 Feb 11;14(3):323-31. doi: 10.1002/cbic.201200706. Epub 2013 Jan 25. Chembiochem. 2013. PMID: 23355266 Free PMC article.

9

Mechanistic heterogeneity in site recognition by the structurally homologous DNA-binding domains of the ETS family transcription factors Ets-1 and PU.1.

Wang S, Linde MH, Munde M, Carvalho VD, Wilson WD, Poon GM. Wang S, et al. J Biol Chem. 2014 Aug 1;289(31):21605-16. doi: 10.1074/jbc.M114.575340. Epub 2014 Jun 21. J Biol Chem. 2014. PMID: 24952944 Free PMC article.

10

Quantitative Investigation of Protein-Nucleic Acid Interactions by Biosensor Surface Plasmon Resonance.

Wang S, Poon GM, Wilson WD. Wang S, et al. Methods Mol Biol. 2015;1334:313-32. doi: 10.1007/978-1-4939-2877-4_20. Methods Mol Biol. 2015. PMID: 26404159 Free PMC article.

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