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Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies.
Diskin R, Klein F, Horwitz JA, Halper-Stromberg A, Sather DN, Marcovecchio PM, Lee T, West AP Jr, Gao H, Seaman MS, Stamatatos L, Nussenzweig MC, Bjorkman PJ. Diskin R, et al. Among authors: seaman ms. J Exp Med. 2013 Jun 3;210(6):1235-49. doi: 10.1084/jem.20130221. Epub 2013 May 27. J Exp Med. 2013. PMID: 23712429 Free PMC article.
A method for identification of HIV gp140 binding memory B cells in human blood.
Scheid JF, Mouquet H, Feldhahn N, Walker BD, Pereyra F, Cutrell E, Seaman MS, Mascola JR, Wyatt RT, Wardemann H, Nussenzweig MC. Scheid JF, et al. Among authors: seaman ms. J Immunol Methods. 2009 Apr 15;343(2):65-7. doi: 10.1016/j.jim.2008.11.012. Epub 2008 Dec 25. J Immunol Methods. 2009. PMID: 19100741 Free PMC article.
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals.
Scheid JF, Mouquet H, Feldhahn N, Seaman MS, Velinzon K, Pietzsch J, Ott RG, Anthony RM, Zebroski H, Hurley A, Phogat A, Chakrabarti B, Li Y, Connors M, Pereyra F, Walker BD, Wardemann H, Ho D, Wyatt RT, Mascola JR, Ravetch JV, Nussenzweig MC. Scheid JF, et al. Among authors: seaman ms. Nature. 2009 Apr 2;458(7238):636-40. doi: 10.1038/nature07930. Epub 2009 Mar 15. Nature. 2009. PMID: 19287373
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation.
Mouquet H, Scheid JF, Zoller MJ, Krogsgaard M, Ott RG, Shukair S, Artyomov MN, Pietzsch J, Connors M, Pereyra F, Walker BD, Ho DD, Wilson PC, Seaman MS, Eisen HN, Chakraborty AK, Hope TJ, Ravetch JV, Wardemann H, Nussenzweig MC. Mouquet H, et al. Among authors: seaman ms. Nature. 2010 Sep 30;467(7315):591-5. doi: 10.1038/nature09385. Nature. 2010. PMID: 20882016 Free PMC article.
Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding.
Scheid JF, Mouquet H, Ueberheide B, Diskin R, Klein F, Oliveira TY, Pietzsch J, Fenyo D, Abadir A, Velinzon K, Hurley A, Myung S, Boulad F, Poignard P, Burton DR, Pereyra F, Ho DD, Walker BD, Seaman MS, Bjorkman PJ, Chait BT, Nussenzweig MC. Scheid JF, et al. Among authors: seaman ms. Science. 2011 Sep 16;333(6049):1633-7. doi: 10.1126/science.1207227. Epub 2011 Jul 14. Science. 2011. PMID: 21764753 Free PMC article.
336 results