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The Nalp3 inflammasome is essential for the development of silicosis.
Cassel SL, Eisenbarth SC, Iyer SS, Sadler JJ, Colegio OR, Tephly LA, Carter AB, Rothman PB, Flavell RA, Sutterwala FS. Cassel SL, et al. Among authors: eisenbarth sc. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9035-40. doi: 10.1073/pnas.0803933105. Epub 2008 Jun 24. Proc Natl Acad Sci U S A. 2008. PMID: 18577586 Free PMC article.
Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy.
Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. Demento SL, et al. Among authors: eisenbarth sc. Vaccine. 2009 May 18;27(23):3013-21. doi: 10.1016/j.vaccine.2009.03.034. Epub 2009 Apr 3. Vaccine. 2009. PMID: 19428913 Free PMC article.
It has recently been shown that one member of an intracellular PRR, the NLRP3 inflammasome, is activated by a number of classical adjuvants including aluminum hydroxide and saponins [Eisenbarth SC, Colegio OR, O'Connor W, Sutterwala FS, Flavell RA. Crucial role for …
It has recently been shown that one member of an intracellular PRR, the NLRP3 inflammasome, is activated by a number of classical adjuvants …
Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M. Shio MT, et al. Among authors: eisenbarth sc. PLoS Pathog. 2009 Aug;5(8):e1000559. doi: 10.1371/journal.ppat.1000559. Epub 2009 Aug 21. PLoS Pathog. 2009. PMID: 19696895 Free PMC article.
Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome.
Iyer SS, Pulskens WP, Sadler JJ, Butter LM, Teske GJ, Ulland TK, Eisenbarth SC, Florquin S, Flavell RA, Leemans JC, Sutterwala FS. Iyer SS, et al. Among authors: eisenbarth sc. Proc Natl Acad Sci U S A. 2009 Dec 1;106(48):20388-93. doi: 10.1073/pnas.0908698106. Epub 2009 Nov 16. Proc Natl Acad Sci U S A. 2009. PMID: 19918053 Free PMC article.
The role of NOD-like Receptors in shaping adaptive immunity.
Williams A, Flavell RA, Eisenbarth SC. Williams A, et al. Among authors: eisenbarth sc. Curr Opin Immunol. 2010 Feb;22(1):34-40. doi: 10.1016/j.coi.2010.01.004. Epub 2010 Feb 9. Curr Opin Immunol. 2010. PMID: 20149616 Free PMC article. Review.
NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, Peaper DR, Bertin J, Eisenbarth SC, Gordon JI, Flavell RA. Elinav E, et al. Among authors: eisenbarth sc. Cell. 2011 May 27;145(5):745-57. doi: 10.1016/j.cell.2011.04.022. Epub 2011 May 12. Cell. 2011. PMID: 21565393 Free PMC article.
105 results