Siegel PM - Search Results

1

The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.

Ahn R, Sabourin V, Ha JR, Cory S, Maric G, Im YK, Hardy WR, Zhao H, Park M, Hallett M, Siegel PM, Pawson T, Ursini-Siegel J. Ahn R, et al. Among authors: siegel pm. Cancer Res. 2013 Jul 15;73(14):4521-32. doi: 10.1158/0008-5472.CAN-12-4178. Epub 2013 May 21. Cancer Res. 2013. PMID: 23695548

2

Novel activating mutations in the neu proto-oncogene involved in induction of mammary tumors.

Siegel PM, Dankort DL, Hardy WR, Muller WJ. Siegel PM, et al. Mol Cell Biol. 1994 Nov;14(11):7068-77. doi: 10.1128/mcb.14.11.7068-7077.1994. Mol Cell Biol. 1994. PMID: 7935422 Free PMC article.

3

Accelerated mammary tumor development in mutant polyomavirus middle T transgenic mice expressing elevated levels of either the Shc or Grb2 adapter protein.

Rauh MJ, Blackmore V, Andrechek ER, Tortorice CG, Daly R, Lai VK, Pawson T, Cardiff RD, Siegel PM, Muller WJ. Rauh MJ, et al. Among authors: siegel pm. Mol Cell Biol. 1999 Dec;19(12):8169-79. doi: 10.1128/MCB.19.12.8169. Mol Cell Biol. 1999. PMID: 10567542 Free PMC article.

4

Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis.

Andrechek ER, Hardy WR, Siegel PM, Rudnicki MA, Cardiff RD, Muller WJ. Andrechek ER, et al. Among authors: siegel pm. Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3444-9. doi: 10.1073/pnas.97.7.3444. Proc Natl Acad Sci U S A. 2000. PMID: 10716706 Free PMC article.

5

Mammary gland neoplasia: insights from transgenic mouse models.

Siegel PM, Hardy WR, Muller WJ. Siegel PM, et al. Bioessays. 2000 Jun;22(6):554-63. doi: 10.1002/(SICI)1521-1878(200006)22:6<554::AID-BIES8>3.0.CO;2-A. Bioessays. 2000. PMID: 10842309 Review.

6

Gene expression profiling of neu-induced mammary tumors from transgenic mice reveals genetic and morphological similarities to ErbB2-expressing human breast cancers.

Andrechek ER, Laing MA, Girgis-Gabardo AA, Siegel PM, Cardiff RD, Muller WJ. Andrechek ER, et al. Among authors: siegel pm. Cancer Res. 2003 Aug 15;63(16):4920-6. Cancer Res. 2003. PMID: 12941816

7

Osteoactivin promotes breast cancer metastasis to bone.

Rose AA, Pepin F, Russo C, Abou Khalil JE, Hallett M, Siegel PM. Rose AA, et al. Among authors: siegel pm. Mol Cancer Res. 2007 Oct;5(10):1001-14. doi: 10.1158/1541-7786.MCR-07-0119. Mol Cancer Res. 2007. PMID: 17951401 Free article.

8

Signaling through ShcA is required for transforming growth factor beta- and Neu/ErbB-2-induced breast cancer cell motility and invasion.

Northey JJ, Chmielecki J, Ngan E, Russo C, Annis MG, Muller WJ, Siegel PM. Northey JJ, et al. Among authors: siegel pm. Mol Cell Biol. 2008 May;28(10):3162-76. doi: 10.1128/MCB.01734-07. Epub 2008 Mar 10. Mol Cell Biol. 2008. PMID: 18332126 Free PMC article.

9

Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer.

Rose AA, Grosset AA, Dong Z, Russo C, Macdonald PA, Bertos NR, St-Pierre Y, Simantov R, Hallett M, Park M, Gaboury L, Siegel PM. Rose AA, et al. Among authors: siegel pm. Clin Cancer Res. 2010 Apr 1;16(7):2147-56. doi: 10.1158/1078-0432.CCR-09-1611. Epub 2010 Mar 9. Clin Cancer Res. 2010. PMID: 20215530

10

ADAM10 releases a soluble form of the GPNMB/Osteoactivin extracellular domain with angiogenic properties.

Rose AA, Annis MG, Dong Z, Pepin F, Hallett M, Park M, Siegel PM. Rose AA, et al. Among authors: siegel pm. PLoS One. 2010 Aug 10;5(8):e12093. doi: 10.1371/journal.pone.0012093. PLoS One. 2010. PMID: 20711474 Free PMC article.

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