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BECLIN1 is essential for intestinal homeostasis involving autophagy-independent mechanisms through its function in endocytic trafficking.
Tran S, Juliani J, Harris TJ, Evangelista M, Ratcliffe J, Ellis SL, Baloyan D, Reehorst CM, Nightingale R, Luk IY, Jenkins LJ, Ghilas S, Yakou MH, Inguanti C, Johnson C, Buchert M, Lee JC, De Cruz P, Duszyc K, Gleeson PA, Kile BT, Mielke LA, Yap AS, Mariadason JM, Fairlie WD, Lee EF. Tran S, et al. Among authors: mielke la. Commun Biol. 2024 Feb 20;7(1):209. doi: 10.1038/s42003-024-05890-7. Commun Biol. 2024. PMID: 38378743 Free PMC article.
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.
Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nuñez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA. Masters SL, et al. Among authors: mielke la. Nat Immunol. 2010 Oct;11(10):897-904. doi: 10.1038/ni.1935. Epub 2010 Sep 12. Nat Immunol. 2010. PMID: 20835230 Free PMC article.
IL-17-producing γδ T cells and innate lymphoid cells.
Sutton CE, Mielke LA, Mills KH. Sutton CE, et al. Among authors: mielke la. Eur J Immunol. 2012 Sep;42(9):2221-31. doi: 10.1002/eji.201242569. Eur J Immunol. 2012. PMID: 22949320 Free article. Review.
Nfil3 is required for the development of all innate lymphoid cell subsets.
Seillet C, Rankin LC, Groom JR, Mielke LA, Tellier J, Chopin M, Huntington ND, Belz GT, Carotta S. Seillet C, et al. Among authors: mielke la. J Exp Med. 2014 Aug 25;211(9):1733-40. doi: 10.1084/jem.20140145. Epub 2014 Aug 4. J Exp Med. 2014. PMID: 25092873 Free PMC article.
54 results