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Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children.
Tolani S, Pagler TA, Murphy AJ, Bochem AE, Abramowicz S, Welch C, Nagareddy PR, Holleran S, Hovingh GK, Kuivenhoven JA, Tall AR. Tolani S, et al. Among authors: abramowicz s. Atherosclerosis. 2013 Jul;229(1):79-85. doi: 10.1016/j.atherosclerosis.2013.03.031. Epub 2013 Apr 19. Atherosclerosis. 2013. PMID: 23684512 Free PMC article. Clinical Trial.
Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.
Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, Tall AR. Westerterp M, et al. Among authors: abramowicz s. Circ Res. 2013 May 24;112(11):1456-65. doi: 10.1161/CIRCRESAHA.113.301086. Epub 2013 Apr 9. Circ Res. 2013. PMID: 23572498 Free PMC article.
Interleukin-3/granulocyte macrophage colony-stimulating factor receptor promotes stem cell expansion, monocytosis, and atheroma macrophage burden in mice with hematopoietic ApoE deficiency.
Wang M, Subramanian M, Abramowicz S, Murphy AJ, Gonen A, Witztum J, Welch C, Tabas I, Westerterp M, Tall AR. Wang M, et al. Among authors: abramowicz s. Arterioscler Thromb Vasc Biol. 2014 May;34(5):976-84. doi: 10.1161/ATVBAHA.113.303097. Epub 2014 Mar 20. Arterioscler Thromb Vasc Biol. 2014. PMID: 24651678 Free PMC article.
Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Endothelial Cells Accelerates Atherosclerosis in Mice.
Westerterp M, Tsuchiya K, Tattersall IW, Fotakis P, Bochem AE, Molusky MM, Ntonga V, Abramowicz S, Parks JS, Welch CL, Kitajewski J, Accili D, Tall AR. Westerterp M, et al. Among authors: abramowicz s. Arterioscler Thromb Vasc Biol. 2016 Jul;36(7):1328-37. doi: 10.1161/ATVBAHA.115.306670. Epub 2016 May 19. Arterioscler Thromb Vasc Biol. 2016. PMID: 27199450 Free PMC article.
TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.
Hsieh J, Koseki M, Molusky MM, Yakushiji E, Ichi I, Westerterp M, Iqbal J, Chan RB, Abramowicz S, Tascau L, Takiguchi S, Yamashita S, Welch CL, Di Paolo G, Hussain MM, Lefkowitch JH, Rader DJ, Tall AR. Hsieh J, et al. Among authors: abramowicz s. Nature. 2016 Jul 14;535(7611):303-7. doi: 10.1038/nature18628. Epub 2016 Jul 6. Nature. 2016. PMID: 27383786 Free PMC article.
159 results