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Page 1
Decreased RyR2 refractoriness determines myocardial synchronization of aberrant Ca2+ release in a genetic model of arrhythmia.
Brunello L, Slabaugh JL, Radwanski PB, Ho HT, Belevych AE, Lou Q, Chen H, Napolitano C, Lodola F, Priori SG, Fedorov VV, Volpe P, Fill M, Janssen PM, Györke S. Brunello L, et al. Among authors: lodola f. Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10312-7. doi: 10.1073/pnas.1300052110. Epub 2013 Jun 3. Proc Natl Acad Sci U S A. 2013. PMID: 23733959 Free PMC article.
CaMKII inhibition rectifies arrhythmic phenotype in a patient-specific model of catecholaminergic polymorphic ventricular tachycardia.
Di Pasquale E, Lodola F, Miragoli M, Denegri M, Avelino-Cruz JE, Buonocore M, Nakahama H, Portararo P, Bloise R, Napolitano C, Condorelli G, Priori SG. Di Pasquale E, et al. Among authors: lodola f. Cell Death Dis. 2013 Oct 10;4(10):e843. doi: 10.1038/cddis.2013.369. Cell Death Dis. 2013. PMID: 24113177 Free PMC article.
Single delivery of an adeno-associated viral construct to transfer the CASQ2 gene to knock-in mice affected by catecholaminergic polymorphic ventricular tachycardia is able to cure the disease from birth to advanced age.
Denegri M, Bongianino R, Lodola F, Boncompagni S, De Giusti VC, Avelino-Cruz JE, Liu N, Persampieri S, Curcio A, Esposito F, Pietrangelo L, Marty I, Villani L, Moyaho A, Baiardi P, Auricchio A, Protasi F, Napolitano C, Priori SG. Denegri M, et al. Among authors: lodola f. Circulation. 2014 Jun 24;129(25):2673-81. doi: 10.1161/CIRCULATIONAHA.113.006901. Epub 2014 Jun 2. Circulation. 2014. PMID: 24888331 Free article.
Adeno-associated virus-mediated CASQ2 delivery rescues phenotypic alterations in a patient-specific model of recessive catecholaminergic polymorphic ventricular tachycardia.
Lodola F, Morone D, Denegri M, Bongianino R, Nakahama H, Rutigliano L, Gosetti R, Rizzo G, Vollero A, Buonocore M, Napolitano C, Condorelli G, Priori SG, Di Pasquale E. Lodola F, et al. Cell Death Dis. 2016 Oct 6;7(10):e2393. doi: 10.1038/cddis.2016.304. Cell Death Dis. 2016. PMID: 27711080 Free PMC article.
Allele-Specific Silencing of Mutant mRNA Rescues Ultrastructural and Arrhythmic Phenotype in Mice Carriers of the R4496C Mutation in the Ryanodine Receptor Gene (RYR2).
Bongianino R, Denegri M, Mazzanti A, Lodola F, Vollero A, Boncompagni S, Fasciano S, Rizzo G, Mangione D, Barbaro S, Di Fonso A, Napolitano C, Auricchio A, Protasi F, Priori SG. Bongianino R, et al. Among authors: lodola f. Circ Res. 2017 Aug 18;121(5):525-536. doi: 10.1161/CIRCRESAHA.117.310882. Epub 2017 Jun 15. Circ Res. 2017. PMID: 28620067
Peptide-Based Targeting of the L-Type Calcium Channel Corrects the Loss-of-Function Phenotype of Two Novel Mutations of the CACNA1 Gene Associated With Brugada Syndrome.
Di Mauro V, Ceriotti P, Lodola F, Salvarani N, Modica J, Bang ML, Mazzanti A, Napolitano C, Priori SG, Catalucci D. Di Mauro V, et al. Among authors: lodola f. Front Physiol. 2021 Jan 8;11:616819. doi: 10.3389/fphys.2020.616819. eCollection 2020. Front Physiol. 2021. PMID: 33488405 Free PMC article.
Ca2+ dysregulation in cardiac stromal cells sustains fibro-adipose remodeling in Arrhythmogenic Cardiomyopathy and can be modulated by flecainide.
Maione AS, Faris P, Iengo L, Catto V, Bisonni L, Lodola F, Negri S, Casella M, Guarino A, Polvani G, Cerrone M, Tondo C, Pompilio G, Sommariva E, Moccia F. Maione AS, et al. Among authors: lodola f. J Transl Med. 2022 Nov 12;20(1):522. doi: 10.1186/s12967-022-03742-8. J Transl Med. 2022. PMID: 36371290 Free PMC article.
48 results