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A self-defeating anabolic program leads to β-cell apoptosis in endoplasmic reticulum stress-induced diabetes via regulation of amino acid flux.
Krokowski D, Han J, Saikia M, Majumder M, Yuan CL, Guan BJ, Bevilacqua E, Bussolati O, Bröer S, Arvan P, Tchórzewski M, Snider MD, Puchowicz M, Croniger CM, Kimball SR, Pan T, Koromilas AE, Kaufman RJ, Hatzoglou M. Krokowski D, et al. Among authors: yuan cl. J Biol Chem. 2013 Jun 14;288(24):17202-13. doi: 10.1074/jbc.M113.466920. Epub 2013 May 3. J Biol Chem. 2013. PMID: 23645676 Free PMC article.
eIF2alpha phosphorylation tips the balance to apoptosis during osmotic stress.
Bevilacqua E, Wang X, Majumder M, Gaccioli F, Yuan CL, Wang C, Zhu X, Jordan LE, Scheuner D, Kaufman RJ, Koromilas AE, Snider MD, Holcik M, Hatzoglou M. Bevilacqua E, et al. Among authors: yuan cl. J Biol Chem. 2010 May 28;285(22):17098-111. doi: 10.1074/jbc.M110.109439. Epub 2010 Mar 25. J Biol Chem. 2010. PMID: 20338999 Free PMC article.
Characterization of hibernating ribosomes in mammalian cells.
Krokowski D, Gaccioli F, Majumder M, Mullins MR, Yuan CL, Papadopoulou B, Merrick WC, Komar AA, Taylor D, Hatzoglou M. Krokowski D, et al. Among authors: yuan cl. Cell Cycle. 2011 Aug 15;10(16):2691-702. doi: 10.4161/cc.10.16.16844. Epub 2011 Aug 15. Cell Cycle. 2011. PMID: 21768774 Free PMC article.
129 results