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105 results

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Page 1
Novel mechanisms of MITF regulation identified in a mouse suppressor screen.
Vu HN, Valdimarsson MM, Sigurbjörnsdóttir S, Bergsteinsdóttir K, Debbache J, Bismuth K, Swing DA, Hallsson JH, Larue L, Arnheiter H, Copeland NG, Jenkins NA, Heidarsson PO, Steingrímsson E. Vu HN, et al. Among authors: steingrimsson e. EMBO Rep. 2024 Oct;25(10):4252-4280. doi: 10.1038/s44319-024-00225-3. Epub 2024 Aug 21. EMBO Rep. 2024. PMID: 39169200 Free PMC article.
An MITF- and mTOR-dependent FLCN pathway suppresses TFE3-driven metastasis in melanoma.
Chang J, Campbell-Hanson KR, Vanneste M, Yevdash J, Bartschat NI, Jiang J, Bhinu A, Helverson A, Henry MD, Steingrímsson E, Weigel RJ, Cornell RA, Kenny C. Chang J, et al. Among authors: steingrimsson e. bioRxiv [Preprint]. 2024 Jul 12:2024.07.11.603140. doi: 10.1101/2024.07.11.603140. bioRxiv. 2024. PMID: 39026725 Free PMC article. Preprint.
ATG7(2) Interacts With Metabolic Proteins and Regulates Central Energy Metabolism.
Ostacolo K, López García de Lomana A, Larat C, Hjaltalin V, Holm KY, Hlynsdóttir SS, Soucheray M, Sooman L, Rolfsson O, Krogan NJ, Steingrimsson E, Swaney DL, Ogmundsdottir MH. Ostacolo K, et al. Among authors: steingrimsson e. Traffic. 2024 Apr;25(4):e12933. doi: 10.1111/tra.12933. Traffic. 2024. PMID: 38600522 Free PMC article.
Novel mechanisms of MITF regulation and melanoma predisposition identified in a mouse suppressor screen.
Vu HN, Valdimarsson MM, Sigurbjörnsdóttir S, Bergsteinsdóttir K, Debbache J, Bismuth K, Swing DA, Hallsson JH, Larue L, Arnheiter H, Copeland NG, Jenkins NA, Heidarsson PO, Steingrímsson E. Vu HN, et al. Among authors: steingrimsson e. bioRxiv [Preprint]. 2023 Aug 4:2023.08.04.551952. doi: 10.1101/2023.08.04.551952. bioRxiv. 2023. Update in: EMBO Rep. 2024 Oct;25(10):4252-4280. doi: 10.1038/s44319-024-00225-3 PMID: 37786677 Free PMC article. Updated. Preprint.
Acetylation reprograms MITF target selectivity and residence time.
Louphrasitthiphol P, Loffreda A, Pogenberg V, Picaud S, Schepsky A, Friedrichsen H, Zeng Z, Lashgari A, Thomas B, Patton EE, Wilmanns M, Filippakopoulos P, Lambert JP, Steingrímsson E, Mazza D, Goding CR. Louphrasitthiphol P, et al. Among authors: steingrimsson e. Nat Commun. 2023 Sep 28;14(1):6051. doi: 10.1038/s41467-023-41793-7. Nat Commun. 2023. PMID: 37770430 Free PMC article.
Germline variants of ATG7 in familial cholangiocarcinoma alter autophagy and p62.
Greer SU, Chen J, Ogmundsdottir MH, Ayala C, Lau BT, Delacruz RGC, Sandoval IT, Kristjansdottir S, Jones DA, Haslem DS, Romero R, Fulde G, Bell JM, Jonasson JG, Steingrimsson E, Ji HP, Nadauld LD. Greer SU, et al. Among authors: steingrimsson e. Sci Rep. 2022 Jun 20;12(1):10333. doi: 10.1038/s41598-022-13569-4. Sci Rep. 2022. PMID: 35725745 Free PMC article.
105 results