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Page 1
CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.
de Graan AJ, Elens L, Sprowl JA, Sparreboom A, Friberg LE, van der Holt B, de Raaf PJ, de Bruijn P, Engels FK, Eskens FA, Wiemer EA, Verweij J, Mathijssen RH, van Schaik RH. de Graan AJ, et al. Among authors: van der holt b, van schaik rh. Clin Cancer Res. 2013 Jun 15;19(12):3316-24. doi: 10.1158/1078-0432.CCR-12-3786. Epub 2013 May 2. Clin Cancer Res. 2013. PMID: 23640974 Free PMC article.
The CYP3A4*3 allele: is it really rare?
van Schaik RH, de Wildt SN, Brosens R, van Fessem M, van den Anker JN, Lindemans J. van Schaik RH, et al. Among authors: van fessem m, van den anker jn. Clin Chem. 2001 Jun;47(6):1104-6. Clin Chem. 2001. PMID: 11375299 No abstract available.
Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.
Hesselink DA, van Gelder T, van Schaik RH, Balk AH, van der Heiden IP, van Dam T, van der Werf M, Weimar W, Mathot RA. Hesselink DA, et al. Among authors: van dam t, van gelder t, van der werf m, van schaik rh, van der heiden ip. Clin Pharmacol Ther. 2004 Dec;76(6):545-56. doi: 10.1016/j.clpt.2004.08.022. Clin Pharmacol Ther. 2004. PMID: 15592326
Factors affecting cytochrome P-450 3A activity in cancer patients.
Baker SD, van Schaik RH, Rivory LP, Ten Tije AJ, Dinh K, Graveland WJ, Schenk PW, Charles KA, Clarke SJ, Carducci MA, McGuire WP, Dawkins F, Gelderblom H, Verweij J, Sparreboom A. Baker SD, et al. Among authors: van schaik rh. Clin Cancer Res. 2004 Dec 15;10(24):8341-50. doi: 10.1158/1078-0432.CCR-04-1371. Clin Cancer Res. 2004. PMID: 15623611
Phase I pharmacokinetic, food effect, and pharmacogenetic study of oral irinotecan given as semisolid matrix capsules in patients with solid tumors.
Soepenberg O, Dumez H, Verweij J, de Jong FA, de Jonge MJ, Thomas J, Eskens FA, van Schaik RH, Selleslach J, Ter Steeg J, Lefebvre P, Assadourian S, Sanderink GJ, Sparreboom A, van Oosterom AT. Soepenberg O, et al. Among authors: van oosterom at, van schaik rh. Clin Cancer Res. 2005 Feb 15;11(4):1504-11. doi: 10.1158/1078-0432.CCR-04-1758. Clin Cancer Res. 2005. PMID: 15746053 Free article. Clinical Trial.
Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients.
Lepper ER, Baker SD, Permenter M, Ries N, van Schaik RH, Schenk PW, Price DK, Ahn D, Smith NF, Cusatis G, Ingersoll RG, Bates SE, Mathijssen RH, Verweij J, Figg WD, Sparreboom A. Lepper ER, et al. Among authors: van schaik rh. Clin Cancer Res. 2005 Oct 15;11(20):7398-404. doi: 10.1158/1078-0432.CCR-05-0520. Clin Cancer Res. 2005. PMID: 16243813 Clinical Trial.
Influence of high-dose ketoconazole on the pharmacokinetics of docetaxel.
Engels FK, Mathot RA, Loos WJ, van Schaik RH, Verweij J. Engels FK, et al. Among authors: van schaik rh. Cancer Biol Ther. 2006 Jul;5(7):833-9. doi: 10.4161/cbt.5.7.2839. Epub 2006 Jul 22. Cancer Biol Ther. 2006. PMID: 16775418 Free article. Clinical Trial.
424 results