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Page 1
CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.
de Graan AJ, Elens L, Sprowl JA, Sparreboom A, Friberg LE, van der Holt B, de Raaf PJ, de Bruijn P, Engels FK, Eskens FA, Wiemer EA, Verweij J, Mathijssen RH, van Schaik RH. de Graan AJ, et al. Among authors: sprowl ja. Clin Cancer Res. 2013 Jun 15;19(12):3316-24. doi: 10.1158/1078-0432.CCR-12-3786. Epub 2013 May 2. Clin Cancer Res. 2013. PMID: 23640974 Free PMC article.
OATP1B2 deficiency protects against paclitaxel-induced neurotoxicity.
Leblanc AF, Sprowl JA, Alberti P, Chiorazzi A, Arnold WD, Gibson AA, Hong KW, Pioso MS, Chen M, Huang KM, Chodisetty V, Costa O, Florea T, de Bruijn P, Mathijssen RH, Reinbolt RE, Lustberg MB, Sucheston-Campbell LE, Cavaletti G, Sparreboom A, Hu S. Leblanc AF, et al. Among authors: sprowl ja. J Clin Invest. 2018 Feb 1;128(2):816-825. doi: 10.1172/JCI96160. Epub 2018 Jan 16. J Clin Invest. 2018. PMID: 29337310 Free PMC article.
Proximal tubular secretion of creatinine by organic cation transporter OCT2 in cancer patients.
Ciarimboli G, Lancaster CS, Schlatter E, Franke RM, Sprowl JA, Pavenstädt H, Massmann V, Guckel D, Mathijssen RH, Yang W, Pui CH, Relling MV, Herrmann E, Sparreboom A. Ciarimboli G, et al. Among authors: sprowl ja. Clin Cancer Res. 2012 Feb 15;18(4):1101-8. doi: 10.1158/1078-0432.CCR-11-2503. Epub 2012 Jan 5. Clin Cancer Res. 2012. PMID: 22223530 Free PMC article.
Human OCT2 variant c.808G>T confers protection effect against cisplatin-induced ototoxicity.
Lanvers-Kaminsky C, Sprowl JA, Malath I, Deuster D, Eveslage M, Schlatter E, Mathijssen RH, Boos J, Jürgens H, Am Zehnhoff-Dinnesen AG, Sparreboom A, Ciarimboli G. Lanvers-Kaminsky C, et al. Among authors: sprowl ja. Pharmacogenomics. 2015;16(4):323-32. doi: 10.2217/pgs.14.182. Pharmacogenomics. 2015. PMID: 25823781 Free PMC article.
Uptake carriers and oncology drug safety.
Sprowl JA, Sparreboom A. Sprowl JA, et al. Drug Metab Dispos. 2014 Apr;42(4):611-22. doi: 10.1124/dmd.113.055806. Epub 2013 Dec 30. Drug Metab Dispos. 2014. PMID: 24378324 Free PMC article. Review.
Can erlotinib ameliorate cisplatin-induced toxicities?
Sprowl JA, Mathijssen RH, Sparreboom A. Sprowl JA, et al. J Clin Oncol. 2013 Sep 20;31(27):3442-3. doi: 10.1200/JCO.2013.50.8184. Epub 2013 Aug 19. J Clin Oncol. 2013. PMID: 23960178 No abstract available.
Polymorphic transporters and platinum pharmacodynamics.
Sprowl JA, Ness RA, Sparreboom A. Sprowl JA, et al. Drug Metab Pharmacokinet. 2013;28(1):19-27. doi: 10.2133/dmpk.dmpk-12-rv-073. Epub 2012 Sep 18. Drug Metab Pharmacokinet. 2013. PMID: 22986709 Free PMC article. Review.
Neuronal uptake transporters contribute to oxaliplatin neurotoxicity in mice.
Huang KM, Leblanc AF, Uddin ME, Kim JY, Chen M, Eisenmann ED, Gibson AA, Li Y, Hong KW, DiGiacomo D, Xia SH, Alberti P, Chiorazzi A, Housley SN, Cope TC, Sprowl JA, Wang J, Loprinzi CL, Noonan A, Lustberg MB, Cavaletti G, Pabla N, Hu S, Sparreboom A. Huang KM, et al. Among authors: sprowl ja. J Clin Invest. 2020 Sep 1;130(9):4601-4606. doi: 10.1172/JCI136796. J Clin Invest. 2020. PMID: 32484793 Free PMC article.
30 results