Brown G - Search Results

1

A caspase-3 'death-switch' in colorectal cancer cells for induced and synchronous tumor apoptosis in vitro and in vivo facilitates the development of minimally invasive cell death biomarkers.

Simpson KL, Cawthorne C, Zhou C, Hodgkinson CL, Walker MJ, Trapani F, Kadirvel M, Brown G, Dawson MJ, MacFarlane M, Williams KJ, Whetton AD, Dive C. Simpson KL, et al. Among authors: brown g. Cell Death Dis. 2013 May 2;4(5):e613. doi: 10.1038/cddis.2013.137. Cell Death Dis. 2013. PMID: 23640455 Free PMC article.

2

[18F]-FLT positron emission tomography can be used to image the response of sensitive tumors to PI3-kinase inhibition with the novel agent GDC-0941.

Cawthorne C, Burrows N, Gieling RG, Morrow CJ, Forster D, Gregory J, Radigois M, Smigova A, Babur M, Simpson K, Hodgkinson C, Brown G, McMahon A, Dive C, Hiscock D, Wilson I, Williams KJ. Cawthorne C, et al. Among authors: brown g. Mol Cancer Ther. 2013 May;12(5):819-28. doi: 10.1158/1535-7163.MCT-12-0905. Epub 2013 Feb 20. Mol Cancer Ther. 2013. PMID: 23427298 Free PMC article.

3

Detection of apoptosis by PET/CT with the diethyl ester of [¹⁸F]ML-10 and fluorescence imaging with a dansyl analogue.

Kadirvel M, Fairclough M, Cawthorne C, Rowling EJ, Babur M, McMahon A, Birkket P, Smigova A, Freeman S, Williams KJ, Brown G. Kadirvel M, et al. Among authors: brown g. Bioorg Med Chem. 2014 Jan 1;22(1):341-9. doi: 10.1016/j.bmc.2013.11.019. Epub 2013 Nov 20. Bioorg Med Chem. 2014. PMID: 24290974

4

N-tert-Prenylation of the indole ring improves the cytotoxicity of a short antagonist G analogue against small cell lung cancer.

Offerman SC, Kadirvel M, Abusara OH, Bryant JL, Telfer BA, Brown G, Freeman S, White A, Williams KJ, Aojula HS. Offerman SC, et al. Among authors: brown g. Medchemcomm. 2017 Feb 17;8(3):551-558. doi: 10.1039/c6md00691d. eCollection 2017 Mar 1. Medchemcomm. 2017. PMID: 30108771 Free PMC article.

5

Radiosynthesis and reactivity of N-[¹¹C]methyl carbamoylimidazole.

Kadirvel M, Cardoso D, Freeman S, Brown G. Kadirvel M, et al. Among authors: brown g. J Radioanal Nucl Chem. 2018;317(2):977-984. doi: 10.1007/s10967-018-5948-4. Epub 2018 Jun 19. J Radioanal Nucl Chem. 2018. PMID: 30100651 Free PMC article.

6

Radiosynthesis of no-carrier-added meta-[¹²⁴I]iodobenzylguanidine for PET imaging of metastatic neuroblastoma.

Green M, Lowe J, Kadirvel M, McMahon A, Westwood N, Chua S, Brown G. Green M, et al. Among authors: brown g. J Radioanal Nucl Chem. 2017;311(1):727-732. doi: 10.1007/s10967-016-5073-1. Epub 2016 Oct 24. J Radioanal Nucl Chem. 2017. PMID: 28111488 Free PMC article.

7

Inhibition of quorum sensing and biofilm formation in Vibrio harveyi by 4-fluoro-DPD; a novel potent inhibitor of signalling.

Kadirvel M, Fanimarvasti F, Forbes S, McBain A, Gardiner JM, Brown GD, Freeman S. Kadirvel M, et al. Chem Commun (Camb). 2014 May 21;50(39):5000-2. doi: 10.1039/c3cc49678c. Chem Commun (Camb). 2014. PMID: 24637781

8

High-Affinity "Click" RGD Peptidomimetics as Radiolabeled Probes for Imaging α_v β₃ Integrin.

Piras M, Testa A, Fleming IN, Dall'Angelo S, Andriu A, Menta S, Mori M, Brown GD, Forster D, Williams KJ, Zanda M. Piras M, et al. ChemMedChem. 2017 Jul 20;12(14):1142-1151. doi: 10.1002/cmdc.201700328. Epub 2017 Jul 3. ChemMedChem. 2017. PMID: 28608961

9

[18F]DPA-714: direct comparison with [11C]PK11195 in a model of cerebral ischemia in rats.

Boutin H, Prenant C, Maroy R, Galea J, Greenhalgh AD, Smigova A, Cawthorne C, Julyan P, Wilkinson SM, Banister SD, Brown G, Herholz K, Kassiou M, Rothwell NJ. Boutin H, et al. Among authors: brown g. PLoS One. 2013;8(2):e56441. doi: 10.1371/journal.pone.0056441. Epub 2013 Feb 13. PLoS One. 2013. PMID: 23418569 Free PMC article.

10

P-glycoprotein expression and function in patients with temporal lobe epilepsy: a case-control study.

Feldmann M, Asselin MC, Liu J, Wang S, McMahon A, Anton-Rodriguez J, Walker M, Symms M, Brown G, Hinz R, Matthews J, Bauer M, Langer O, Thom M, Jones T, Vollmar C, Duncan JS, Sisodiya SM, Koepp MJ. Feldmann M, et al. Among authors: brown g. Lancet Neurol. 2013 Aug;12(8):777-85. doi: 10.1016/S1474-4422(13)70109-1. Epub 2013 Jun 18. Lancet Neurol. 2013. PMID: 23786896

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