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Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain.
Arbel-Ornath M, Hudry E, Boivin JR, Hashimoto T, Takeda S, Kuchibhotla KV, Hou S, Lattarulo CR, Belcher AM, Shakerdge N, Trujillo PB, Muzikansky A, Betensky RA, Hyman BT, Bacskai BJ. Arbel-Ornath M, et al. Among authors: hashimoto t. Mol Neurodegener. 2017 Mar 21;12(1):27. doi: 10.1186/s13024-017-0169-9. Mol Neurodegener. 2017. PMID: 28327181 Free PMC article.
Oligomeric amyloid beta associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques.
Koffie RM, Meyer-Luehmann M, Hashimoto T, Adams KW, Mielke ML, Garcia-Alloza M, Micheva KD, Smith SJ, Kim ML, Lee VM, Hyman BT, Spires-Jones TL. Koffie RM, et al. Among authors: hashimoto t. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):4012-7. doi: 10.1073/pnas.0811698106. Epub 2009 Feb 19. Proc Natl Acad Sci U S A. 2009. PMID: 19228947 Free PMC article.
Brain oligomeric β-amyloid but not total amyloid plaque burden correlates with neuronal loss and astrocyte inflammatory response in amyloid precursor protein/tau transgenic mice.
DaRocha-Souto B, Scotton TC, Coma M, Serrano-Pozo A, Hashimoto T, Serenó L, Rodríguez M, Sánchez B, Hyman BT, Gómez-Isla T. DaRocha-Souto B, et al. Among authors: hashimoto t. J Neuropathol Exp Neurol. 2011 May;70(5):360-76. doi: 10.1097/NEN.0b013e318217a118. J Neuropathol Exp Neurol. 2011. PMID: 21487307 Free PMC article.
7,015 results