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Inhibition of AMPK catabolic action by GSK3.
Suzuki T, Bridges D, Nakada D, Skiniotis G, Morrison SJ, Lin JD, Saltiel AR, Inoki K. Suzuki T, et al. Among authors: skiniotis g. Mol Cell. 2013 May 9;50(3):407-19. doi: 10.1016/j.molcel.2013.03.022. Epub 2013 Apr 25. Mol Cell. 2013. PMID: 23623684 Free PMC article.
Structure determination of inactive-state GPCRs with a universal nanobody.
Robertson MJ, Papasergi-Scott MM, He F, Seven AB, Meyerowitz JG, Panova O, Peroto MC, Che T, Skiniotis G. Robertson MJ, et al. Among authors: skiniotis g. Nat Struct Mol Biol. 2022 Dec;29(12):1188-1195. doi: 10.1038/s41594-022-00859-8. Epub 2022 Nov 17. Nat Struct Mol Biol. 2022. PMID: 36396979
Insights into distinct signaling profiles of the µOR activated by diverse agonists.
Qu Q, Huang W, Aydin D, Paggi JM, Seven AB, Wang H, Chakraborty S, Che T, DiBerto JF, Robertson MJ, Inoue A, Suomivuori CM, Roth BL, Majumdar S, Dror RO, Kobilka BK, Skiniotis G. Qu Q, et al. Among authors: skiniotis g. Nat Chem Biol. 2023 Apr;19(4):423-430. doi: 10.1038/s41589-022-01208-y. Epub 2022 Nov 21. Nat Chem Biol. 2023. PMID: 36411392 Free PMC article.
Allosteric modulation and G-protein selectivity of the Ca2+-sensing receptor.
He F, Wu CG, Gao Y, Rahman SN, Zaoralová M, Papasergi-Scott MM, Gu TJ, Robertson MJ, Seven AB, Li L, Mathiesen JM, Skiniotis G. He F, et al. Among authors: skiniotis g. Nature. 2024 Feb;626(8001):1141-1148. doi: 10.1038/s41586-024-07055-2. Epub 2024 Feb 7. Nature. 2024. PMID: 38326620
Structural basis for activation of CB1 by an endocannabinoid analog.
Krishna Kumar K, Robertson MJ, Thadhani E, Wang H, Suomivuori CM, Powers AS, Ji L, Nikas SP, Dror RO, Inoue A, Makriyannis A, Skiniotis G, Kobilka B. Krishna Kumar K, et al. Among authors: skiniotis g. Nat Commun. 2023 May 9;14(1):2672. doi: 10.1038/s41467-023-37864-4. Nat Commun. 2023. PMID: 37160876 Free PMC article.
Ligand-induced architecture of the leptin receptor signaling complex.
Mancour LV, Daghestani HN, Dutta S, Westfield GH, Schilling J, Oleskie AN, Herbstman JF, Chou SZ, Skiniotis G. Mancour LV, et al. Among authors: skiniotis g. Mol Cell. 2012 Nov 30;48(4):655-61. doi: 10.1016/j.molcel.2012.09.003. Epub 2012 Oct 11. Mol Cell. 2012. PMID: 23063524 Free PMC article.
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Among authors: skiniotis g. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.
126 results