Hercus TR - Search Results

1

Characterization of pathogenic human monoclonal autoantibodies against GM-CSF.

Wang Y, Thomson CA, Allan LL, Jackson LM, Olson M, Hercus TR, Nero TL, Turner A, Parker MW, Lopez AL, Waddell TK, Anderson GP, Hamilton JA, Schrader JW. Wang Y, et al. Among authors: hercus tr. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7832-7. doi: 10.1073/pnas.1216011110. Epub 2013 Apr 25. Proc Natl Acad Sci U S A. 2013. PMID: 23620516 Free PMC article.

2

Specific human granulocyte-macrophage colony-stimulating factor antagonists.

Hercus TR, Bagley CJ, Cambareri B, Dottore M, Woodcock JM, Vadas MA, Shannon MF, Lopez AF. Hercus TR, et al. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):5838-42. doi: 10.1073/pnas.91.13.5838. Proc Natl Acad Sci U S A. 1994. PMID: 8016076 Free PMC article.

3

Crucial role of the residue R280 at the F'-G' loop of the human granulocyte/macrophage colony-stimulating factor receptor alpha chain for ligand recognition.

Rajotte D, Cadieux C, Haman A, Wilkes BC, Clark SC, Hercus T, Woodcock JA, Lopez A, Hoang T. Rajotte D, et al. J Exp Med. 1997 Jun 2;185(11):1939-50. doi: 10.1084/jem.185.11.1939. J Exp Med. 1997. PMID: 9166423 Free PMC article.

4

Molecular determinants of the granulocyte-macrophage colony-stimulating factor receptor complex assembly.

Haman A, Cadieux C, Wilkes B, Hercus T, Lopez A, Clark S, Hoang T. Haman A, et al. J Biol Chem. 1999 Nov 26;274(48):34155-63. doi: 10.1074/jbc.274.48.34155. J Biol Chem. 1999. PMID: 10567387 Free article.

5

Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common beta-chain bound to an antagonist.

Rossjohn J, McKinstry WJ, Woodcock JM, McClure BJ, Hercus TR, Parker MW, Lopez AF, Bagley CJ. Rossjohn J, et al. Among authors: hercus tr. Blood. 2000 Apr 15;95(8):2491-8. Blood. 2000. PMID: 10753826 Free article.

6

A phase I study of the GM-CSF antagonist E21R.

Olver IN, Hercus T, Lopez A, Vadas M, Somogyi AA, Doyle I, Foster DJ, Keefe D, Taylor A, Brown M, To LB, Cole J, Rawling T, Cambareri B, Myers M, Olszewski N, Bastiras S, Senn C, Hey A, Verma M, Wigley P. Olver IN, et al. Cancer Chemother Pharmacol. 2002 Sep;50(3):171-8. doi: 10.1007/s00280-002-0474-y. Epub 2002 Jul 3. Cancer Chemother Pharmacol. 2002. PMID: 12203098 Clinical Trial.

7

Crystallization and preliminary X-ray diffraction analysis of the ternary human GM-CSF receptor complex.

Hansen G, Hercus TR, Xu Y, Lopez AF, Parker MW, McKinstry WJ. Hansen G, et al. Among authors: hercus tr. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Aug 1;64(Pt 8):711-4. doi: 10.1107/S1744309108019404. Epub 2008 Jul 5. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18678938 Free PMC article.

8

The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation.

Hansen G, Hercus TR, McClure BJ, Stomski FC, Dottore M, Powell J, Ramshaw H, Woodcock JM, Xu Y, Guthridge M, McKinstry WJ, Lopez AF, Parker MW. Hansen G, et al. Among authors: hercus tr. Cell. 2008 Aug 8;134(3):496-507. doi: 10.1016/j.cell.2008.05.053. Cell. 2008. PMID: 18692472 Free article.

9

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease.

Hercus TR, Thomas D, Guthridge MA, Ekert PG, King-Scott J, Parker MW, Lopez AF. Hercus TR, et al. Blood. 2009 Aug 13;114(7):1289-98. doi: 10.1182/blood-2008-12-164004. Epub 2009 May 12. Blood. 2009. PMID: 19436055 Free PMC article. Review.

10

Molecular basis of cytokine receptor activation.

Lopez AF, Hercus TR, Ekert P, Littler DR, Guthridge M, Thomas D, Ramshaw HS, Stomski F, Perugini M, D'Andrea R, Grimbaldeston M, Parker MW. Lopez AF, et al. Among authors: hercus tr. IUBMB Life. 2010 Jul;62(7):509-18. doi: 10.1002/iub.350. IUBMB Life. 2010. PMID: 20540154 Free article. Review.

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