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Treatment with P28GST, a schistosome-derived enzyme, after acute colitis induction in mice: Decrease of intestinal inflammation associated with a down regulation of Th1/Th17 responses.
Sarazin A, Dendooven A, Delbeke M, Gatault S, Pagny A, Standaert A, Rousseaux C, Desreumaux P, Dubuquoy L, Capron M. Sarazin A, et al. PLoS One. 2018 Dec 28;13(12):e0209681. doi: 10.1371/journal.pone.0209681. eCollection 2018. PLoS One. 2018. PMID: 30592734 Free PMC article.
The schistosome glutathione S-transferase P28GST, a unique helminth protein, prevents intestinal inflammation in experimental colitis through a Th2-type response with mucosal eosinophils.
Driss V, El Nady M, Delbeke M, Rousseaux C, Dubuquoy C, Sarazin A, Gatault S, Dendooven A, Riveau G, Colombel JF, Desreumaux P, Dubuquoy L, Capron M. Driss V, et al. Among authors: sarazin a. Mucosal Immunol. 2016 Mar;9(2):322-35. doi: 10.1038/mi.2015.62. Epub 2015 Jul 15. Mucosal Immunol. 2016. PMID: 26174763 Free PMC article.
42 results