Fang D - Search Results

1

The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression.

Chan KM, Fang D, Gan H, Hashizume R, Yu C, Schroeder M, Gupta N, Mueller S, James CD, Jenkins R, Sarkaria J, Zhang Z. Chan KM, et al. Among authors: fang d. Genes Dev. 2013 May 1;27(9):985-90. doi: 10.1101/gad.217778.113. Epub 2013 Apr 19. Genes Dev. 2013. PMID: 23603901 Free PMC article.

2

A lesson learned from the H3.3K27M mutation found in pediatric glioma: a new approach to the study of the function of histone modifications in vivo?

Chan KM, Han J, Fang D, Gan H, Zhang Z. Chan KM, et al. Among authors: fang d. Cell Cycle. 2013 Aug 15;12(16):2546-52. doi: 10.4161/cc.25625. Epub 2013 Jul 10. Cell Cycle. 2013. PMID: 23907119 Free PMC article.

3

Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.

Hashizume R, Andor N, Ihara Y, Lerner R, Gan H, Chen X, Fang D, Huang X, Tom MW, Ngo V, Solomon D, Mueller S, Paris PL, Zhang Z, Petritsch C, Gupta N, Waldman TA, James CD. Hashizume R, et al. Among authors: fang d. Nat Med. 2014 Dec;20(12):1394-6. doi: 10.1038/nm.3716. Epub 2014 Nov 17. Nat Med. 2014. PMID: 25401693 Free PMC article.

4

The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas.

Fang D, Gan H, Lee JH, Han J, Wang Z, Riester SM, Jin L, Chen J, Zhou H, Wang J, Zhang H, Yang N, Bradley EW, Ho TH, Rubin BP, Bridge JA, Thibodeau SN, Ordog T, Chen Y, van Wijnen AJ, Oliveira AM, Xu RM, Westendorf JJ, Zhang Z. Fang D, et al. Science. 2016 Jun 10;352(6291):1344-8. doi: 10.1126/science.aae0065. Epub 2016 May 26. Science. 2016. PMID: 27229140 Free PMC article.

5

Probe the function of histone lysine 36 methylation using histone H3 lysine 36 to methionine mutant transgene in mammalian cells.

Fang D, Gan H, Wang H, Zhou H, Zhang Z. Fang D, et al. Cell Cycle. 2017 Oct 2;16(19):1781-1789. doi: 10.1080/15384101.2017.1281483. Epub 2017 Jan 27. Cell Cycle. 2017. PMID: 28129023 Free PMC article.

6

Live-cell single-molecule dynamics of PcG proteins imposed by the DIPG H3.3K27M mutation.

Tatavosian R, Duc HN, Huynh TN, Fang D, Schmitt B, Shi X, Deng Y, Phiel C, Yao T, Zhang Z, Wang H, Ren X. Tatavosian R, et al. Among authors: fang d. Nat Commun. 2018 May 25;9(1):2080. doi: 10.1038/s41467-018-04455-7. Nat Commun. 2018. PMID: 29802243 Free PMC article.

7

H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers.

Fang D, Gan H, Cheng L, Lee JH, Zhou H, Sarkaria JN, Daniels DJ, Zhang Z. Fang D, et al. Elife. 2018 Jun 22;7:e36696. doi: 10.7554/eLife.36696. Elife. 2018. PMID: 29932419 Free PMC article.

8

A novel enhancer regulates MGMT expression and promotes temozolomide resistance in glioblastoma.

Chen X, Zhang M, Gan H, Wang H, Lee JH, Fang D, Kitange GJ, He L, Hu Z, Parney IF, Meyer FB, Giannini C, Sarkaria JN, Zhang Z. Chen X, et al. Among authors: fang d. Nat Commun. 2018 Jul 27;9(1):2949. doi: 10.1038/s41467-018-05373-4. Nat Commun. 2018. PMID: 30054476 Free PMC article.

9

Probing the Function of Oncohistones Using Mutant Transgenes and Knock-In Mutations.

Fang D, Wang H, Zhang Z. Fang D, et al. Methods Mol Biol. 2018;1832:339-356. doi: 10.1007/978-1-4939-8663-7_19. Methods Mol Biol. 2018. PMID: 30073537

10

The incorporation loci of H3.3K36M determine its preferential prevalence in chondroblastomas.

Zhang Y, Fang D. Zhang Y, et al. Among authors: fang d. Cell Death Dis. 2021 Mar 24;12(4):311. doi: 10.1038/s41419-021-03597-9. Cell Death Dis. 2021. PMID: 33762579 Free PMC article.

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