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Superresolution imaging of amyloid fibrils with binding-activated probes.
Ries J, Udayar V, Soragni A, Hornemann S, Nilsson KP, Riek R, Hock C, Ewers H, Aguzzi AA, Rajendran L. Ries J, et al. Among authors: riek r. ACS Chem Neurosci. 2013 Jul 17;4(7):1057-61. doi: 10.1021/cn400091m. Epub 2013 Apr 22. ACS Chem Neurosci. 2013. PMID: 23594172 Free PMC article.
In vivo demonstration that alpha-synuclein oligomers are toxic.
Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, Pham E, Masliah E, Gage FH, Riek R. Winner B, et al. Among authors: riek r. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4194-9. doi: 10.1073/pnas.1100976108. Epub 2011 Feb 15. Proc Natl Acad Sci U S A. 2011. PMID: 21325059 Free PMC article.
Mechanism of membrane interaction and disruption by α-synuclein.
Reynolds NP, Soragni A, Rabe M, Verdes D, Liverani E, Handschin S, Riek R, Seeger S. Reynolds NP, et al. Among authors: riek r. J Am Chem Soc. 2011 Dec 7;133(48):19366-75. doi: 10.1021/ja2029848. Epub 2011 Nov 9. J Am Chem Soc. 2011. PMID: 21978222
Binding of Polythiophenes to Amyloids: Structural Mapping of the Pharmacophore.
Schütz AK, Hornemann S, Wälti MA, Greuter L, Tiberi C, Cadalbert R, Gantner M, Riek R, Hammarström P, Nilsson KPR, Böckmann A, Aguzzi A, Meier BH. Schütz AK, et al. Among authors: riek r. ACS Chem Neurosci. 2018 Mar 21;9(3):475-481. doi: 10.1021/acschemneuro.7b00397. Epub 2017 Dec 4. ACS Chem Neurosci. 2018. PMID: 29178774
Functional amyloids as natural storage of peptide hormones in pituitary secretory granules.
Maji SK, Perrin MH, Sawaya MR, Jessberger S, Vadodaria K, Rissman RA, Singru PS, Nilsson KP, Simon R, Schubert D, Eisenberg D, Rivier J, Sawchenko P, Vale W, Riek R. Maji SK, et al. Among authors: riek r. Science. 2009 Jul 17;325(5938):328-32. doi: 10.1126/science.1173155. Epub 2009 Jun 18. Science. 2009. PMID: 19541956 Free PMC article.
The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein.
Sonati T, Reimann RR, Falsig J, Baral PK, O'Connor T, Hornemann S, Yaganoglu S, Li B, Herrmann US, Wieland B, Swayampakula M, Rahman MH, Das D, Kav N, Riek R, Liberski PP, James MN, Aguzzi A. Sonati T, et al. Among authors: riek r. Nature. 2013 Sep 5;501(7465):102-6. doi: 10.1038/nature12402. Epub 2013 Jul 31. Nature. 2013. PMID: 23903654 Free article.
267 results