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Superresolution imaging of amyloid fibrils with binding-activated probes.
Ries J, Udayar V, Soragni A, Hornemann S, Nilsson KP, Riek R, Hock C, Ewers H, Aguzzi AA, Rajendran L. Ries J, et al. Among authors: nilsson kp. ACS Chem Neurosci. 2013 Jul 17;4(7):1057-61. doi: 10.1021/cn400091m. Epub 2013 Apr 22. ACS Chem Neurosci. 2013. PMID: 23594172 Free PMC article.
Prion strain discrimination using luminescent conjugated polymers.
Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Polymenidou M, Schwarz P, Leclerc M, Hammarström P, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. Among authors: nilsson kp. Nat Methods. 2007 Dec;4(12):1023-30. doi: 10.1038/nmeth1131. Epub 2007 Nov 18. Nat Methods. 2007. PMID: 18026110
Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses.
Aslund A, Sigurdson CJ, Klingstedt T, Grathwohl S, Bolmont T, Dickstein DL, Glimsdal E, Prokop S, Lindgren M, Konradsson P, Holtzman DM, Hof PR, Heppner FL, Gandy S, Jucker M, Aguzzi A, Hammarström P, Nilsson KP. Aslund A, et al. Among authors: nilsson kp. ACS Chem Biol. 2009 Aug 21;4(8):673-84. doi: 10.1021/cb900112v. ACS Chem Biol. 2009. PMID: 19624097 Free PMC article.
A molecular switch controls interspecies prion disease transmission in mice.
Sigurdson CJ, Nilsson KP, Hornemann S, Manco G, Fernández-Borges N, Schwarz P, Castilla J, Wüthrich K, Aguzzi A. Sigurdson CJ, et al. Among authors: nilsson kp. J Clin Invest. 2010 Jul;120(7):2590-9. doi: 10.1172/JCI42051. Epub 2010 Jun 14. J Clin Invest. 2010. PMID: 20551516 Free PMC article.
Structure-based drug design identifies polythiophenes as antiprion compounds.
Herrmann US, Schütz AK, Shirani H, Huang D, Saban D, Nuvolone M, Li B, Ballmer B, Åslund AK, Mason JJ, Rushing E, Budka H, Nyström S, Hammarström P, Böckmann A, Caflisch A, Meier BH, Nilsson KP, Hornemann S, Aguzzi A. Herrmann US, et al. Among authors: nilsson kp. Sci Transl Med. 2015 Aug 5;7(299):299ra123. doi: 10.1126/scitranslmed.aab1923. Sci Transl Med. 2015. PMID: 26246168
Binding of Polythiophenes to Amyloids: Structural Mapping of the Pharmacophore.
Schütz AK, Hornemann S, Wälti MA, Greuter L, Tiberi C, Cadalbert R, Gantner M, Riek R, Hammarström P, Nilsson KPR, Böckmann A, Aguzzi A, Meier BH. Schütz AK, et al. ACS Chem Neurosci. 2018 Mar 21;9(3):475-481. doi: 10.1021/acschemneuro.7b00397. Epub 2017 Dec 4. ACS Chem Neurosci. 2018. PMID: 29178774
159 results