De Silva SR - Search Results

1

Assessment of tropism and effectiveness of new primate-derived hybrid recombinant AAV serotypes in the mouse and primate retina.

Charbel Issa P, De Silva SR, Lipinski DM, Singh MS, Mouravlev A, You Q, Barnard AR, Hankins MW, During MJ, Maclaren RE. Charbel Issa P, et al. Among authors: de silva sr. PLoS One. 2013 Apr 9;8(4):e60361. doi: 10.1371/journal.pone.0060361. Print 2013. PLoS One. 2013. PMID: 23593201 Free PMC article.

2

Functional expression of Rab escort protein 1 following AAV2-mediated gene delivery in the retina of choroideremia mice and human cells ex vivo.

Tolmachova T, Tolmachov OE, Barnard AR, de Silva SR, Lipinski DM, Walker NJ, Maclaren RE, Seabra MC. Tolmachova T, et al. Among authors: de silva sr. J Mol Med (Berl). 2013 Jul;91(7):825-37. doi: 10.1007/s00109-013-1006-4. Epub 2013 Jun 12. J Mol Med (Berl). 2013. PMID: 23756766 Free PMC article.

3

Vesicular stomatitis virus glycoprotein- and Venezuelan equine encephalitis virus-derived glycoprotein-pseudotyped lentivirus vectors differentially transduce corneal endothelium, trabecular meshwork, and human photoreceptors.

Lipinski DM, Barnard AR, Charbel Issa P, Singh MS, De Silva SR, Trabalza A, Eleftheriadou I, Ellison SM, Mazarakis ND, MacLaren RE. Lipinski DM, et al. Among authors: de silva sr. Hum Gene Ther. 2014 Jan;25(1):50-62. doi: 10.1089/hum.2013.009. Epub 2013 Dec 21. Hum Gene Ther. 2014. PMID: 24125177

4

Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4^-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo.

De Silva SR, Charbel Issa P, Singh MS, Lipinski DM, Barnea-Cramer AO, Walker NJ, Barnard AR, Hankins MW, MacLaren RE. De Silva SR, et al. Gene Ther. 2016 Nov;23(11):767-774. doi: 10.1038/gt.2016.54. Epub 2016 Jul 14. Gene Ther. 2016. PMID: 27416076 Free PMC article.

5

Tropism of engineered and evolved recombinant AAV serotypes in the rd1 mouse and ex vivo primate retina.

Hickey DG, Edwards TL, Barnard AR, Singh MS, de Silva SR, McClements ME, Flannery JG, Hankins MW, MacLaren RE. Hickey DG, et al. Among authors: de silva sr. Gene Ther. 2017 Dec;24(12):787-800. doi: 10.1038/gt.2017.85. Epub 2017 Nov 16. Gene Ther. 2017. PMID: 28872643 Free PMC article.

6

Long-term restoration of visual function in end-stage retinal degeneration using subretinal human melanopsin gene therapy.

De Silva SR, Barnard AR, Hughes S, Tam SKE, Martin C, Singh MS, Barnea-Cramer AO, McClements ME, During MJ, Peirson SN, Hankins MW, MacLaren RE. De Silva SR, et al. Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11211-11216. doi: 10.1073/pnas.1701589114. Epub 2017 Oct 2. Proc Natl Acad Sci U S A. 2017. PMID: 28973921 Free PMC article.

7

Human Retinal Explant Culture for Ex Vivo Validation of AAV Gene Therapy.

Orlans HO, Edwards TL, De Silva SR, Patrício MI, MacLaren RE. Orlans HO, et al. Among authors: de silva sr. Methods Mol Biol. 2018;1715:289-303. doi: 10.1007/978-1-4939-7522-8_21. Methods Mol Biol. 2018. PMID: 29188522

8

Improved Diagnosis of Retinal Laser Injuries Using Near-Infrared Autofluorescence.

De Silva SR, Neffendorf JE, Birtel J, Herrmann P, Downes SM, Patel CK, Hildebrand GD, Gliem M, Charbel Issa P. De Silva SR, et al. Am J Ophthalmol. 2019 Dec;208:87-93. doi: 10.1016/j.ajo.2019.06.001. Epub 2019 Jun 12. Am J Ophthalmol. 2019. PMID: 31199894

9

Repair of Retinal Degeneration following Ex Vivo Minicircle DNA Gene Therapy and Transplantation of Corrected Photoreceptor Progenitors.

Barnea-Cramer AO, Singh M, Fischer D, De Silva S, McClements ME, Barnard AR, MacLaren RE. Barnea-Cramer AO, et al. Mol Ther. 2020 Mar 4;28(3):830-844. doi: 10.1016/j.ymthe.2020.01.023. Epub 2020 Jan 29. Mol Ther. 2020. PMID: 32027843 Free PMC article.

10

The Role of Inflammation in Age-Related Macular Degeneration-Therapeutic Landscapes in Geographic Atrophy.

Borchert GA, Shamsnajafabadi H, Hu ML, De Silva SR, Downes SM, MacLaren RE, Xue K, Cehajic-Kapetanovic J. Borchert GA, et al. Among authors: de silva sr. Cells. 2023 Aug 18;12(16):2092. doi: 10.3390/cells12162092. Cells. 2023. PMID: 37626902 Free PMC article. Review.

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