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Simulation-based evaluation of the Pharmpy Automatic Model Development tool for population pharmacokinetic modeling in early clinical drug development.
Duvnjak Z, Schaedeli Stark F, Cosson V, Retout S, Schindler E, Abrantes JA. Duvnjak Z, et al. Among authors: schaedeli stark f. CPT Pharmacometrics Syst Pharmacol. 2024 Oct;13(10):1707-1721. doi: 10.1002/psp4.13213. Epub 2024 Aug 18. CPT Pharmacometrics Syst Pharmacol. 2024. PMID: 39155545 Free PMC article.
Population Pharmacokinetic and Exposure-dizziness Modeling for a Metabotropic Glutamate Receptor Subtype 5 Negative Allosteric Modulator in Major Depressive Disorder Patients.
Cosson V, Schaedeli-Stark F, Arab-Alameddine M, Chavanne C, Guerini E, Derks M, Mallalieu NL. Cosson V, et al. Among authors: schaedeli stark f. Clin Transl Sci. 2018 Sep;11(5):523-531. doi: 10.1111/cts.12566. Epub 2018 Jun 27. Clin Transl Sci. 2018. PMID: 29877614 Free PMC article. Clinical Trial.
Phase I trial of capecitabine rapidly disintegrating tablets and concomitant radiation therapy in children with newly diagnosed brainstem gliomas and high-grade gliomas.
Kilburn LB, Kocak M, Schaedeli Stark F, Meneses-Lorente G, Brownstein C, Hussain S, Chintagumpala M, Thompson PA, Gururangan S, Banerjee A, Paulino AC, Kun L, Boyett JM, Blaney SM. Kilburn LB, et al. Among authors: schaedeli stark f. Neuro Oncol. 2013 Jun;15(6):759-66. doi: 10.1093/neuonc/nos315. Epub 2013 Apr 16. Neuro Oncol. 2013. PMID: 23592571 Free PMC article. Clinical Trial.
A population pharmacokinetic/pharmacodynamic model of thrombocytopenia characterizing the effect of trastuzumab emtansine (T-DM1) on platelet counts in patients with HER2-positive metastatic breast cancer.
Bender BC, Schaedeli-Stark F, Koch R, Joshi A, Chu YW, Rugo H, Krop IE, Girish S, Friberg LE, Gupta M. Bender BC, et al. Among authors: schaedeli stark f. Cancer Chemother Pharmacol. 2012 Oct;70(4):591-601. doi: 10.1007/s00280-012-1934-7. Epub 2012 Aug 12. Cancer Chemother Pharmacol. 2012. PMID: 22886072 Clinical Trial.