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EPI-743 reverses the progression of the pediatric mitochondrial disease--genetically defined Leigh Syndrome.
Martinelli D, Catteruccia M, Piemonte F, Pastore A, Tozzi G, Dionisi-Vici C, Pontrelli G, Corsetti T, Livadiotti S, Kheifets V, Hinman A, Shrader WD, Thoolen M, Klein MB, Bertini E, Miller G. Martinelli D, et al. Among authors: klein mb. Mol Genet Metab. 2012 Nov;107(3):383-8. doi: 10.1016/j.ymgme.2012.09.007. Epub 2012 Sep 10. Mol Genet Metab. 2012. PMID: 23010433 Clinical Trial.
Japanese Leigh syndrome case treated with EPI-743.
Kouga T, Takagi M, Miyauchi A, Shimbo H, Iai M, Yamashita S, Murayama K, Klein MB, Miller G, Goto T, Osaka H. Kouga T, et al. Among authors: klein mb. Brain Dev. 2018 Feb;40(2):145-149. doi: 10.1016/j.braindev.2017.08.005. Epub 2017 Sep 12. Brain Dev. 2018. PMID: 28916229
Targeting ferroptosis: A novel therapeutic strategy for the treatment of mitochondrial disease-related epilepsy.
Kahn-Kirby AH, Amagata A, Maeder CI, Mei JJ, Sideris S, Kosaka Y, Hinman A, Malone SA, Bruegger JJ, Wang L, Kim V, Shrader WD, Hoff KG, Latham JC, Ashley EA, Wheeler MT, Bertini E, Carrozzo R, Martinelli D, Dionisi-Vici C, Chapman KA, Enns GM, Gahl W, Wolfe L, Saneto RP, Johnson SC, Trimmer JK, Klein MB, Holst CR. Kahn-Kirby AH, et al. Among authors: klein mb. PLoS One. 2019 Mar 28;14(3):e0214250. doi: 10.1371/journal.pone.0214250. eCollection 2019. PLoS One. 2019. PMID: 30921410 Free PMC article.
Double-blind, randomized and controlled trial of EPI-743 in Friedreich's ataxia.
Zesiewicz T, Salemi JL, Perlman S, Sullivan KL, Shaw JD, Huang Y, Isaacs C, Gooch C, Lynch DR, Klein MB. Zesiewicz T, et al. Among authors: klein mb. Neurodegener Dis Manag. 2018 Aug;8(4):233-242. doi: 10.2217/nmt-2018-0013. Epub 2018 Jul 27. Neurodegener Dis Manag. 2018. PMID: 30051753 Clinical Trial.
Unsuccessful Direct Acting Antiviral Hepatitis C Treatment Among People With HIV: Findings From an International Cohort.
Harney BL, Sacks-Davis R, van Santen DK, Stewart AC, Matthews GV, Carson JM, Klein MB, Lacombe K, Wittkop L, Salmon D, Leleux O, Merchadou L, van der Valk M, Smit C, Prins M, Boyd A, Berenguer J, Jarrin I, Rauch A, Hellard ME, Doyle JS. Harney BL, et al. Among authors: klein mb. Liver Int. 2025 Jan;45(1):1-13. doi: 10.1111/liv.16203. Liver Int. 2025. PMID: 39656170 Free PMC article.
Perceived patient navigator services and characteristics to address barriers to linkage to hepatitis C care among people released from provincial prison in Quebec, Canada.
Kronfli N, Mambro A, Riback LR, Ortiz-Paredes D, Dussault C, Chalifoux S, Del Balso L, Petropoulos A, Lim M, Halavrezos A, Sebastiani G, Klein MB, Lebouche B, Cox J, Akiyama MJ. Kronfli N, et al. Among authors: klein mb. Int J Drug Policy. 2024 Nov;133:104624. doi: 10.1016/j.drugpo.2024.104624. Epub 2024 Oct 18. Int J Drug Policy. 2024. PMID: 39426103 Free article.
457 results