Ridgway RA - Search Results

1

Bone marrow injection stimulates hepatic ductular reactions in the absence of injury via macrophage-mediated TWEAK signaling.

Bird TG, Lu WY, Boulter L, Gordon-Keylock S, Ridgway RA, Williams MJ, Taube J, Thomas JA, Wojtacha D, Gambardella A, Sansom OJ, Iredale JP, Forbes SJ. Bird TG, et al. Among authors: ridgway ra. Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6542-7. doi: 10.1073/pnas.1302168110. Epub 2013 Apr 1. Proc Natl Acad Sci U S A. 2013. PMID: 23576749 Free PMC article.

2

The pro-apoptotic K-Ras 4A proto-oncoprotein does not affect tumorigenesis in the ApcMin/+ mouse small intestine.

Patek CE, Arends MJ, Rose L, Luo F, Walker M, Devenney PS, Berry RL, Lawrence NJ, Ridgway RA, Sansom OJ, Hooper ML. Patek CE, et al. Among authors: ridgway ra. BMC Gastroenterol. 2008 Jun 13;8:24. doi: 10.1186/1471-230X-8-24. BMC Gastroenterol. 2008. PMID: 18554389 Free PMC article.

3

Peptide combinatorial libraries identify TSC2 as a death-associated protein kinase (DAPK) death domain-binding protein and reveal a stimulatory role for DAPK in mTORC1 signaling.

Stevens C, Lin Y, Harrison B, Burch L, Ridgway RA, Sansom O, Hupp T. Stevens C, et al. Among authors: ridgway ra. J Biol Chem. 2009 Jan 2;284(1):334-344. doi: 10.1074/jbc.M805165200. Epub 2008 Oct 30. J Biol Chem. 2009. PMID: 18974095 Free article.

4

B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver.

Reed KR, Athineos D, Meniel VS, Wilkins JA, Ridgway RA, Burke ZD, Muncan V, Clarke AR, Sansom OJ. Reed KR, et al. Among authors: ridgway ra. Proc Natl Acad Sci U S A. 2008 Dec 2;105(48):18919-23. doi: 10.1073/pnas.0805778105. Epub 2008 Nov 24. Proc Natl Acad Sci U S A. 2008. PMID: 19033191 Free PMC article.

5

Mutant p53 drives metastasis and overcomes growth arrest/senescence in pancreatic cancer.

Morton JP, Timpson P, Karim SA, Ridgway RA, Athineos D, Doyle B, Jamieson NB, Oien KA, Lowy AM, Brunton VG, Frame MC, Evans TR, Sansom OJ. Morton JP, et al. Among authors: ridgway ra. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):246-51. doi: 10.1073/pnas.0908428107. Epub 2009 Dec 14. Proc Natl Acad Sci U S A. 2010. PMID: 20018721 Free PMC article.

6

Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.

Cole AM, Myant K, Reed KR, Ridgway RA, Athineos D, Van den Brink GR, Muncan V, Clevers H, Clarke AR, Sicinski P, Sansom OJ. Cole AM, et al. Among authors: ridgway ra. Cancer Res. 2010 Oct 15;70(20):8149-58. doi: 10.1158/0008-5472.CAN-10-0315. Epub 2010 Aug 24. Cancer Res. 2010. PMID: 20736363 Free PMC article.

7

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease.

Boulter L, Govaere O, Bird TG, Radulescu S, Ramachandran P, Pellicoro A, Ridgway RA, Seo SS, Spee B, Van Rooijen N, Sansom OJ, Iredale JP, Lowell S, Roskams T, Forbes SJ. Boulter L, et al. Among authors: ridgway ra. Nat Med. 2012 Mar 4;18(4):572-9. doi: 10.1038/nm.2667. Nat Med. 2012. PMID: 22388089 Free PMC article.

8

Methods to assess Myc function in intestinal homeostasis, regeneration, and tumorigenesis.

Huels DJ, Cammareri P, Ridgway RA, Medema JP, Sansom OJ. Huels DJ, et al. Among authors: ridgway ra. Methods Mol Biol. 2013;1012:237-48. doi: 10.1007/978-1-62703-429-6_16. Methods Mol Biol. 2013. PMID: 24006069

9

The APC network regulates the removal of mutated cells from colonic crypts.

Song JH, Huels DJ, Ridgway RA, Sansom OJ, Kholodenko BN, Kolch W, Cho KH. Song JH, et al. Among authors: ridgway ra. Cell Rep. 2014 Apr 10;7(1):94-103. doi: 10.1016/j.celrep.2014.02.043. Epub 2014 Mar 27. Cell Rep. 2014. PMID: 24685131 Free article.

10

c-Src drives intestinal regeneration and transformation.

Cordero JB, Ridgway RA, Valeri N, Nixon C, Frame MC, Muller WJ, Vidal M, Sansom OJ. Cordero JB, et al. Among authors: ridgway ra. EMBO J. 2014 Jul 1;33(13):1474-91. doi: 10.1002/embj.201387454. Epub 2014 Apr 30. EMBO J. 2014. PMID: 24788409 Free PMC article.

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