Yue P - Search Results

1

The PI3 kinase inhibitor NVP-BKM120 induces GSK3/FBXW7-dependent Mcl-1 degradation, contributing to induction of apoptosis and enhancement of TRAIL-induced apoptosis.

Ren H, Zhao L, Li Y, Yue P, Deng X, Owonikoko TK, Chen M, Khuri FR, Sun SY. Ren H, et al. Among authors: yue p. Cancer Lett. 2013 Sep 28;338(2):229-38. doi: 10.1016/j.canlet.2013.03.032. Epub 2013 Apr 2. Cancer Lett. 2013. PMID: 23562472 Free PMC article.

2

The combination of RAD001 and NVP-BKM120 synergistically inhibits the growth of lung cancer in vitro and in vivo.

Ren H, Chen M, Yue P, Tao H, Owonikoko TK, Ramalingam SS, Khuri FR, Sun SY. Ren H, et al. Among authors: yue p. Cancer Lett. 2012 Dec 28;325(2):139-46. doi: 10.1016/j.canlet.2012.06.018. Epub 2012 Jul 7. Cancer Lett. 2012. PMID: 22781393 Free PMC article.

3

mTOR complex 2 is involved in regulation of Cbl-dependent c-FLIP degradation and sensitivity of TRAIL-induced apoptosis.

Zhao L, Yue P, Khuri FR, Sun SY. Zhao L, et al. Among authors: yue p. Cancer Res. 2013 Mar 15;73(6):1946-57. doi: 10.1158/0008-5472.CAN-12-3710. Epub 2013 Jan 14. Cancer Res. 2013. PMID: 23319802 Free PMC article.

4

The E3 ubiquitin ligases β-TrCP and FBXW7 cooperatively mediates GSK3-dependent Mcl-1 degradation induced by the Akt inhibitor API-1, resulting in apoptosis.

Ren H, Koo J, Guan B, Yue P, Deng X, Chen M, Khuri FR, Sun SY. Ren H, et al. Among authors: yue p. Mol Cancer. 2013 Nov 22;12:146. doi: 10.1186/1476-4598-12-146. Mol Cancer. 2013. PMID: 24261825 Free PMC article.

5

Enhancing therapeutic efficacy of the MEK inhibitor, MEK162, by blocking autophagy or inhibiting PI3K/Akt signaling in human lung cancer cells.

Yao W, Yue P, Zhang G, Owonikoko TK, Khuri FR, Sun SY. Yao W, et al. Among authors: yue p. Cancer Lett. 2015 Aug 1;364(1):70-8. doi: 10.1016/j.canlet.2015.04.028. Epub 2015 Apr 29. Cancer Lett. 2015. PMID: 25937299 Free PMC article.

6

The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition.

Yao W, Yue P, Khuri FR, Sun SY. Yao W, et al. Among authors: yue p. Oncotarget. 2015 Oct 27;6(33):34669-79. doi: 10.18632/oncotarget.5785. Oncotarget. 2015. PMID: 26415225 Free PMC article.

7

Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.

Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. Shi P, et al. Among authors: yue p. Cancer Lett. 2016 Oct 1;380(2):494-504. doi: 10.1016/j.canlet.2016.07.021. Epub 2016 Jul 19. Cancer Lett. 2016. PMID: 27450722

8

p53 upregulates death receptor 4 expression through an intronic p53 binding site.

Liu X, Yue P, Khuri FR, Sun SY. Liu X, et al. Among authors: yue p. Cancer Res. 2004 Aug 1;64(15):5078-83. doi: 10.1158/0008-5472.CAN-04-1195. Cancer Res. 2004. PMID: 15289308

9

c-Jun NH2-terminal kinase-mediated up-regulation of death receptor 5 contributes to induction of apoptosis by the novel synthetic triterpenoid methyl-2-cyano-3,12-dioxooleana-1, 9-dien-28-oate in human lung cancer cells.

Zou W, Liu X, Yue P, Zhou Z, Sporn MB, Lotan R, Khuri FR, Sun SY. Zou W, et al. Among authors: yue p. Cancer Res. 2004 Oct 15;64(20):7570-8. doi: 10.1158/0008-5472.CAN-04-1238. Cancer Res. 2004. PMID: 15492284

10

Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells.

Liu X, Yue P, Zhou Z, Khuri FR, Sun SY. Liu X, et al. Among authors: yue p. J Natl Cancer Inst. 2004 Dec 1;96(23):1769-80. doi: 10.1093/jnci/djh322. J Natl Cancer Inst. 2004. PMID: 15572759

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