Bordas M - Search Results

1

Synthesis and biological evaluation of a new series of hexahydro-2H-pyrano[3,2-c]quinolines as novel selective σ1 receptor ligands.

Díaz JL, Christmann U, Fernández A, Luengo M, Bordas M, Enrech R, Carro M, Pascual R, Burgueño J, Merlos M, Benet-Buchholz J, Cerón-Bertran J, Ramírez J, Reinoso RF, Fernández de Henestrosa AR, Vela JM, Almansa C. Díaz JL, et al. Among authors: bordas m. J Med Chem. 2013 May 9;56(9):3656-65. doi: 10.1021/jm400181k. Epub 2013 Apr 26. J Med Chem. 2013. PMID: 23560650

2

Critical comparison of shake-flask, potentiometric and chromatographic methods for lipophilicity evaluation (log P_o/w) of neutral, acidic, basic, amphoteric, and zwitterionic drugs.

Port A, Bordas M, Enrech R, Pascual R, Rosés M, Ràfols C, Subirats X, Bosch E. Port A, et al. Among authors: bordas m. Eur J Pharm Sci. 2018 Sep 15;122:331-340. doi: 10.1016/j.ejps.2018.07.010. Epub 2018 Jul 10. Eur J Pharm Sci. 2018. PMID: 30006180 Free article.

3

Pyrazolo[3,4-d]pyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 2: Introduction of cyclic substituents in position 4.

Díaz JL, Corbera J, Martínez D, Bordas M, Sicre C, Pascual R, Pretel MJ, Marín AP, Montero A, Dordal A, Alvarez I, Almansa C. Díaz JL, et al. Among authors: bordas m. Medchemcomm. 2017 Apr 20;8(6):1246-1254. doi: 10.1039/c7md00078b. eCollection 2017 Jun 1. Medchemcomm. 2017. PMID: 30108835 Free PMC article.

4

Discovery of EST73502, a Dual μ-Opioid Receptor Agonist and σ₁ Receptor Antagonist Clinical Candidate for the Treatment of Pain.

García M, Virgili M, Alonso M, Alegret C, Farran J, Fernández B, Bordas M, Pascual R, Burgueño J, Vidal-Torres A, Fernández de Henestrosa AR, Ayet E, Merlos M, Vela JM, Plata-Salamán CR, Almansa C. García M, et al. Among authors: bordas m. J Med Chem. 2020 Dec 24;63(24):15508-15526. doi: 10.1021/acs.jmedchem.0c01127. Epub 2020 Oct 16. J Med Chem. 2020. PMID: 33064947

5

Propionamide Derivatives as Dual μ-Opioid Receptor Agonists and σ₁ Receptor Antagonists for the Treatment of Pain.

García M, Llorente V, Garriga L, Christmann U, Rodríguez-Escrich S, Virgili M, Fernández B, Bordas M, Ayet E, Burgueño J, Pujol M, Dordal A, Portillo-Salido E, Gris G, Vela JM, Almansa C. García M, et al. Among authors: bordas m. J Med Chem. 2021 Jul 22;64(14):10139-10154. doi: 10.1021/acs.jmedchem.1c00417. Epub 2021 Jul 8. J Med Chem. 2021. PMID: 34236190

6

Discovery of WLB-89462, a New Drug-like and Highly Selective σ₂ Receptor Ligand with Neuroprotective Properties.

Christmann U, Díaz JL, Pascual R, Bordas M, Álvarez I, Monroy X, Porras M, Yeste S, Reinoso RF, Merlos M, Vela JM, Almansa C. Christmann U, et al. Among authors: bordas m. J Med Chem. 2023 Sep 14;66(17):12499-12519. doi: 10.1021/acs.jmedchem.3c01060. Epub 2023 Aug 22. J Med Chem. 2023. PMID: 37607512

7

WLB-87848, a Selective σ₁ Receptor Agonist, with an Unusually Positioned NH Group as Positive Ionizable Moiety and Showing Neuroprotective Activity.

Christmann U, Garriga L, Llorente AV, Díaz JL, Pascual R, Bordas M, Dordal A, Porras M, Yeste S, Reinoso RF, Vela JM, Almansa C. Christmann U, et al. Among authors: bordas m. J Med Chem. 2024 Jun 13;67(11):9150-9164. doi: 10.1021/acs.jmedchem.4c00288. Epub 2024 May 16. J Med Chem. 2024. PMID: 38753759

8

Occurrence of heterocyclic amines in several home-cooked meat dishes of the Spanish diet.

Busquets R, Bordas M, Toribio F, Puignou L, Galceran MT. Busquets R, et al. Among authors: bordas m. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Mar 25;802(1):79-86. doi: 10.1016/j.jchromb.2003.09.033. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15035999

9

Formation and stability of heterocyclic amines in a meat flavour model system. Effect of temperature, time and precursors.

Bordas M, Moyano E, Puignou L, Galceran MT. Bordas M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Mar 25;802(1):11-7. doi: 10.1016/j.jchromb.2003.09.024. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 15035992

10

Lipid droplets and small extracellular vesicles: More than two independent entities.

Genard GC, Tirinato L, Pagliari F, Da Silva J, Giammona A, Alquraish F, Reyes MP, Bordas M, Marafioti MG, Franco SD, Janssen J, Garcia-Calderón D, Hanley R, Nistico C, Fukasawa Y, Müller T, Krijgsveld J, Todaro M, Costanzo FS, Stassi G, Nessling M, Richter K, Maass KK, Liberale C, Seco J. Genard GC, et al. Among authors: bordas m. J Extracell Biol. 2024 Sep 10;3(9):e162. doi: 10.1002/jex2.162. eCollection 2024 Sep. J Extracell Biol. 2024. PMID: 39257626 Free PMC article.

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