Holland KD - Search Results

1

Physiological regulation of the picrotoxin receptor by gamma-butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons.

Holland KD, Ferrendelli JA, Covey DF, Rothman SM. Holland KD, et al. J Neurosci. 1990 Jun;10(6):1719-27. doi: 10.1523/JNEUROSCI.10-06-01719.1990. J Neurosci. 1990. PMID: 2355246 Free PMC article.

2

Relative anticonvulsant effects of GABAmimetic and GABA modulatory agents.

Holland KD, McKeon AC, Canney DJ, Covey DF, Ferrendelli JA. Holland KD, et al. Epilepsia. 1992 Nov-Dec;33(6):981-6. doi: 10.1111/j.1528-1157.1992.tb01747.x. Epilepsia. 1992. PMID: 1334454

3

Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist.

Holland KD, Yoon KW, Ferrendelli JA, Covey DF, Rothman SM. Holland KD, et al. Mol Pharmacol. 1991 Jan;39(1):79-84. Mol Pharmacol. 1991. PMID: 1846222

4

Synthesis and structure-activity studies of alkyl-substituted gamma-butyrolactones and gamma-thiobutyrolactones: ligands for the picrotoxin receptor.

Canney DJ, Holland KD, Levine JA, McKeon AC, Ferrendelli JA, Covey DF. Canney DJ, et al. Among authors: holland kd. J Med Chem. 1991 Apr;34(4):1460-7. doi: 10.1021/jm00108a034. J Med Chem. 1991. PMID: 1849999

5

Physiological modulation of the GABA receptor by convulsant and anticonvulsant barbiturates in cultured rat hippocampal neurons.

Holland KD, Canney DJ, Rothman SM, Ferrendelli JA, Covey DF. Holland KD, et al. Brain Res. 1990 May 14;516(1):147-50. doi: 10.1016/0006-8993(90)90910-4. Brain Res. 1990. PMID: 2163720

6

Binding interactions of convulsant and anticonvulsant gamma-butyrolactones and gamma-thiobutyrolactones with the picrotoxin receptor.

Holland KD, McKeon AC, Covey DF, Ferrendelli JA. Holland KD, et al. J Pharmacol Exp Ther. 1990 Aug;254(2):578-83. J Pharmacol Exp Ther. 1990. PMID: 2166797

7

Comparison of the anticonvulsant activities of ethosuximide, valproate, and a new anticonvulsant, thiobutyrolactone.

Ferrendelli JA, Holland KD, McKeon AC, Covey DF. Ferrendelli JA, et al. Among authors: holland kd. Epilepsia. 1989 Sep-Oct;30(5):617-22. doi: 10.1111/j.1528-1157.1989.tb05482.x. Epilepsia. 1989. PMID: 2507307

8

Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones.

Holland KD, Mathews GC, Bolos-Sy AM, Tucker JB, Reddy PA, Covey DF, Ferrendelli JA, Rothman SM. Holland KD, et al. Mol Pharmacol. 1995 Jun;47(6):1217-23. Mol Pharmacol. 1995. PMID: 7603463

9

Developmental alteration in GABAA receptor structure and physiological properties in cultured cerebellar granule neurons.

Mathews GC, Bolos-Sy AM, Holland KD, Isenberg KE, Covey DF, Ferrendelli JA, Rothman SM. Mathews GC, et al. Among authors: holland kd. Neuron. 1994 Jul;13(1):149-58. doi: 10.1016/0896-6273(94)90465-0. Neuron. 1994. PMID: 8043274

10

Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones.

Peterson EM, Xu K, Holland KD, McKeon AC, Rothman SM, Ferrendelli JA, Covey DF. Peterson EM, et al. Among authors: holland kd. J Med Chem. 1994 Jan 21;37(2):275-86. doi: 10.1021/jm00028a011. J Med Chem. 1994. PMID: 8295215

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