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A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.
Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, Zhuang L, Hudak S, Rees DG, Goldberg D, Barton C, Chang L, Vainshtein I, Liang M, Iciek L, Ambery P, Peakman M, Vaughan TJ, Tree TI, Sansom DM, Bowen MA, Minter RR, Jermutus L. Douthwaite J, et al. Among authors: sabbah s. J Immunol. 2017 Jan 1;198(1):528-537. doi: 10.4049/jimmunol.1600682. Epub 2016 Nov 23. J Immunol. 2017. PMID: 27881707
Autoreactive T cell profiles are altered following allogeneic islet transplantation with alemtuzumab induction and re-emerging phenotype is associated with graft function.
Sabbah S, Liew A, Brooks AM, Kundu R, Reading JL, Flatt A, Counter C, Choudhary P, Forbes S, Rosenthal MJ, Rutter MK, Cairns S, Johnson P, Casey J, Peakman M, Shaw JA, Tree TIM. Sabbah S, et al. Am J Transplant. 2021 Mar;21(3):1027-1038. doi: 10.1111/ajt.16285. Epub 2020 Sep 19. Am J Transplant. 2021. PMID: 32865886 Free article.
Physiological and pathogenic T cell autoreactivity converge in type 1 diabetes.
Eugster A, Lorenc A, Kotrulev M, Kamra Y, Goel M, Steinberg-Bains K, Sabbah S, Dietz S, Bonifacio E, Peakman M, Gomez-Tourino I. Eugster A, et al. Among authors: sabbah s. Nat Commun. 2024 Oct 29;15(1):9204. doi: 10.1038/s41467-024-53255-9. Nat Commun. 2024. PMID: 39472557 Free PMC article.
Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.
Douthwaite J, Moisan J, Privezentzev C, Soskic B, Sabbah S, Cohen S, Collinson A, England E, Huntington C, Kemp B, Zhuang L, Hudak S, Rees DG, Goldberg D, Barton C, Chang L, Vainshtein I, Liang M, Iciek L, Ambery P, Peakman M, Vaughan TJ, Tree TIM, Sansom DM, Bowen MA, Minter RR, Jermutus L. Douthwaite J, et al. Among authors: sabbah s. J Immunol. 2017 Sep 1;199(5):1943. doi: 10.4049/jimmunol.1790013. J Immunol. 2017. PMID: 28827388 No abstract available.
90 results