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Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.
Reeves JT, Fandrick DR, Tan Z, Song JJ, Rodriguez S, Qu B, Kim S, Niemeier O, Li Z, Byrne D, Campbell S, Chitroda A, DeCroos P, Fachinger T, Fuchs V, Gonnella NC, Grinberg N, Haddad N, Jäger B, Lee H, Lorenz JC, Ma S, Narayanan BA, Nummy LJ, Premasiri A, Roschangar F, Sarvestani M, Shen S, Spinelli E, Sun X, Varsolona RJ, Yee N, Brenner M, Senanayake CH. Reeves JT, et al. J Org Chem. 2013 Apr 19;78(8):3616-35. doi: 10.1021/jo400079z. Epub 2013 Apr 1. J Org Chem. 2013. PMID: 23544738
Asymmetric synthesis of active pharmaceutical ingredients.
Farina V, Reeves JT, Senanayake CH, Song JJ. Farina V, et al. Among authors: reeves jt. Chem Rev. 2006 Jul;106(7):2734-93. doi: 10.1021/cr040700c. Chem Rev. 2006. PMID: 16836298 Review. No abstract available.
N-heterocyclic carbene-catalyzed silyl enol ether formation.
Song JJ, Tan Z, Reeves JT, Fandrick DR, Yee NK, Senanayake CH. Song JJ, et al. Among authors: reeves jt. Org Lett. 2008 Mar 6;10(5):877-80. doi: 10.1021/ol703025b. Epub 2008 Jan 31. Org Lett. 2008. PMID: 18232703
357 results