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Sulfone-Mediated SNAr Reaction as a Powerful Tool for the Synthesis of 4-Quinolinyl Ethers and More-Application to the Synthesis of HCV NS3/4a Protease Inhibitor BI 201420.
Patel ND, Wei X, Byrne D, Narayanan BA, Pennino S, Sarvestani M, Saha A, Haddad N, Kapadia S, Lorenz JC, DeCroos P, Ye A, Lee H, Grinberg N, Hossain A, Busacca CA, Yee NK, Senanayake CH. Patel ND, et al. Among authors: decroos p. J Org Chem. 2020 Jul 2;85(13):8339-8351. doi: 10.1021/acs.joc.0c00554. Epub 2020 Jun 19. J Org Chem. 2020. PMID: 32462862
Design and synthesis of chiral oxathiozinone scaffolds: efficient synthesis of hindered enantiopure sulfinamides and sulfinyl ketimines.
Han ZS, Herbage MA, Mangunuru HP, Xu Y, Zhang L, Reeves JT, Sieber JD, Li Z, DeCroos P, Zhang Y, Li G, Li N, Ma S, Grinberg N, Wang X, Goyal N, Krishnamurthy D, Lu B, Song JJ, Wang G, Senanayake CH. Han ZS, et al. Among authors: decroos p. Angew Chem Int Ed Engl. 2013 Jun 24;52(26):6713-7. doi: 10.1002/anie.201301676. Epub 2013 May 15. Angew Chem Int Ed Engl. 2013. PMID: 23677810 No abstract available.
Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.
Reeves JT, Fandrick DR, Tan Z, Song JJ, Rodriguez S, Qu B, Kim S, Niemeier O, Li Z, Byrne D, Campbell S, Chitroda A, DeCroos P, Fachinger T, Fuchs V, Gonnella NC, Grinberg N, Haddad N, Jäger B, Lee H, Lorenz JC, Ma S, Narayanan BA, Nummy LJ, Premasiri A, Roschangar F, Sarvestani M, Shen S, Spinelli E, Sun X, Varsolona RJ, Yee N, Brenner M, Senanayake CH. Reeves JT, et al. Among authors: decroos p. J Org Chem. 2013 Apr 19;78(8):3616-35. doi: 10.1021/jo400079z. Epub 2013 Apr 1. J Org Chem. 2013. PMID: 23544738