Lakshmana MK - Search Results

1

Striking reduction of amyloid plaque burden in an Alzheimer's mouse model after chronic administration of carmustine.

Hayes CD, Dey D, Palavicini JP, Wang H, Patkar KA, Minond D, Nefzi A, Lakshmana MK. Hayes CD, et al. Among authors: lakshmana mk. BMC Med. 2013 Mar 26;11:81. doi: 10.1186/1741-7015-11-81. BMC Med. 2013. PMID: 23531149 Free PMC article.

2

Chronic cladribine administration increases amyloid beta peptide generation and plaque burden in mice.

Hayes CD, Dey D, Palavicini JP, Wang H, Araki W, Lakshmana MK. Hayes CD, et al. Among authors: lakshmana mk. PLoS One. 2012;7(10):e45841. doi: 10.1371/journal.pone.0045841. Epub 2012 Oct 3. PLoS One. 2012. PMID: 23056220 Free PMC article.

3

RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer's brain synaptosomes.

Palavicini JP, Wang H, Bianchi E, Xu S, Rao JS, Kang DE, Lakshmana MK. Palavicini JP, et al. Among authors: lakshmana mk. Cell Death Dis. 2013 Jun 13;4(6):e667. doi: 10.1038/cddis.2013.183. Cell Death Dis. 2013. PMID: 23764848 Free PMC article.

4

COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels.

Wang H, Dey D, Carrera I, Minond D, Bianchi E, Xu S, Lakshmana MK. Wang H, et al. Among authors: lakshmana mk. J Biol Chem. 2013 Sep 13;288(37):26668-77. doi: 10.1074/jbc.M113.476689. Epub 2013 Aug 7. J Biol Chem. 2013. PMID: 23926111 Free PMC article.

5

RanBP9 overexpression down-regulates phospho-cofilin, causes early synaptic deficits and impaired learning, and accelerates accumulation of amyloid plaques in the mouse brain.

Palavicini JP, Wang H, Minond D, Bianchi E, Xu S, Lakshmana MK. Palavicini JP, et al. Among authors: lakshmana mk. J Alzheimers Dis. 2014;39(4):727-40. doi: 10.3233/JAD-131550. J Alzheimers Dis. 2014. PMID: 24254706

6

AlphaLISA-based high-throughput screening assay to measure levels of soluble amyloid precursor protein α.

Wang H, Nefzi A, Fields GB, Lakshmana MK, Minond D. Wang H, et al. Among authors: lakshmana mk. Anal Biochem. 2014 Aug 15;459:24-30. doi: 10.1016/j.ab.2014.05.007. Epub 2014 May 20. Anal Biochem. 2014. PMID: 24857774

7

RanBP9 overexpression accelerates loss of dendritic spines in a mouse model of Alzheimer's disease.

Wang R, Palavicini JP, Wang H, Maiti P, Bianchi E, Xu S, Lloyd BN, Dawson-Scully K, Kang DE, Lakshmana MK. Wang R, et al. Among authors: lakshmana mk. Neurobiol Dis. 2014 Sep;69:169-79. doi: 10.1016/j.nbd.2014.05.029. Epub 2014 Jun 2. Neurobiol Dis. 2014. PMID: 24892886 Free PMC article.

8

Substituted dithiazole piperazine benzamides as novel amyloid beta peptide reducing agents.

Wang H, Wang R, Lakshmana MK, Nefzi A. Wang H, et al. Among authors: lakshmana mk. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4384-4388. doi: 10.1016/j.bmcl.2014.08.022. Epub 2014 Aug 13. Bioorg Med Chem Lett. 2014. PMID: 25155386 Free PMC article.

9

COPS5 protein overexpression increases amyloid plaque burden, decreases spinophilin-immunoreactive puncta, and exacerbates learning and memory deficits in the mouse brain.

Wang R, Wang H, Carrera I, Xu S, Lakshmana MK. Wang R, et al. Among authors: lakshmana mk. J Biol Chem. 2015 Apr 3;290(14):9299-309. doi: 10.1074/jbc.M114.595926. Epub 2015 Feb 20. J Biol Chem. 2015. PMID: 25713139 Free PMC article.

10

Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain.

Lakshmana MK, Hayes CD, Bennett SP, Bianchi E, Reddy KM, Koo EH, Kang DE. Lakshmana MK, et al. FASEB J. 2012 May;26(5):2072-83. doi: 10.1096/fj.11-196709. Epub 2012 Jan 31. FASEB J. 2012. PMID: 22294787 Free PMC article.

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