Kagechika H - Search Results

1

Structures of histone methyltransferase SET7/9 in complexes with adenosylmethionine derivatives.

Niwa H, Handa N, Tomabechi Y, Honda K, Toyama M, Ohsawa N, Shirouzu M, Kagechika H, Hirano T, Umehara T, Yokoyama S. Niwa H, et al. Among authors: kagechika h. Acta Crystallogr D Biol Crystallogr. 2013 Apr;69(Pt 4):595-602. doi: 10.1107/S0907444912052092. Epub 2013 Mar 14. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23519668

2

Development of a library of 6-arylcoumarins as candidate fluorescent sensors.

Hirano T, Hiromoto K, Kagechika H. Hirano T, et al. Among authors: kagechika h. Org Lett. 2007 Mar 29;9(7):1315-8. doi: 10.1021/ol070142z. Epub 2007 Feb 28. Org Lett. 2007. PMID: 17326649

3

Novel thyroid hormone receptor antagonists with an N-alkylated diphenylamine skeleton.

Komatsu T, Hirano T, Songkram C, Kawachi E, Kagechika H. Komatsu T, et al. Among authors: kagechika h. Bioorg Med Chem. 2007 May 1;15(9):3115-26. doi: 10.1016/j.bmc.2007.02.053. Epub 2007 Mar 3. Bioorg Med Chem. 2007. PMID: 17363258

4

Thyromimetics: a review of recent reports and patents (2004 - 2009).

Hirano T, Kagechika H. Hirano T, et al. Among authors: kagechika h. Expert Opin Ther Pat. 2010 Feb;20(2):213-28. doi: 10.1517/13543770903567069. Expert Opin Ther Pat. 2010. PMID: 20100003 Review.

5

Modulation of intramolecular heterodimer-induced fluorescence quenching of tricarbocyanine dye for the development of fluorescent sensor.

Hirano T, Akiyama J, Mori S, Kagechika H. Hirano T, et al. Among authors: kagechika h. Org Biomol Chem. 2010 Dec 21;8(24):5568-75. doi: 10.1039/c0ob00207k. Epub 2010 Oct 8. Org Biomol Chem. 2010. PMID: 20931144

6

Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9.

Mori S, Iwase K, Iwanami N, Tanaka Y, Kagechika H, Hirano T. Mori S, et al. Among authors: kagechika h. Bioorg Med Chem. 2010 Dec 1;18(23):8158-66. doi: 10.1016/j.bmc.2010.10.022. Epub 2010 Oct 14. Bioorg Med Chem. 2010. PMID: 21036620

7

6-arylcoumarins as novel nonsteroidal type progesterone antagonists: an example with receptor-binding-dependent fluorescence.

Sakai H, Hirano T, Mori S, Fujii S, Masuno H, Kinoshita M, Kagechika H, Tanatani A. Sakai H, et al. Among authors: kagechika h. J Med Chem. 2011 Oct 27;54(20):7055-65. doi: 10.1021/jm2005404. Epub 2011 Oct 5. J Med Chem. 2011. PMID: 21916484

8

Identification of Cyproheptadine as an Inhibitor of SET Domain Containing Lysine Methyltransferase 7/9 (Set7/9) That Regulates Estrogen-Dependent Transcription.

Takemoto Y, Ito A, Niwa H, Okamura M, Fujiwara T, Hirano T, Handa N, Umehara T, Sonoda T, Ogawa K, Tariq M, Nishino N, Dan S, Kagechika H, Yamori T, Yokoyama S, Yoshida M. Takemoto Y, et al. Among authors: kagechika h. J Med Chem. 2016 Apr 28;59(8):3650-60. doi: 10.1021/acs.jmedchem.5b01732. Epub 2016 Apr 18. J Med Chem. 2016. PMID: 27088648

9

Steric structure-activity relationship of cyproheptadine derivatives as inhibitors of histone methyltransferase Set7/9.

Fujiwara T, Ohira K, Urushibara K, Ito A, Yoshida M, Kanai M, Tanatani A, Kagechika H, Hirano T. Fujiwara T, et al. Among authors: kagechika h. Bioorg Med Chem. 2016 Sep 15;24(18):4318-4323. doi: 10.1016/j.bmc.2016.07.024. Epub 2016 Jul 12. Bioorg Med Chem. 2016. PMID: 27448773

10

Development of Novel Inhibitors for Histone Methyltransferase SET7/9 based on Cyproheptadine.

Hirano T, Fujiwara T, Niwa H, Hirano M, Ohira K, Okazaki Y, Sato S, Umehara T, Maemoto Y, Ito A, Yoshida M, Kagechika H. Hirano T, et al. Among authors: kagechika h. ChemMedChem. 2018 Aug 10;13(15):1530-1540. doi: 10.1002/cmdc.201800233. Epub 2018 Jul 6. ChemMedChem. 2018. PMID: 29882380

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