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β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.
Cai J, Qi X, Kociok N, Skosyrski S, Emilio A, Ruan Q, Han S, Liu L, Chen Z, Bowes Rickman C, Golde T, Grant MB, Saftig P, Serneels L, de Strooper B, Joussen AM, Boulton ME. Cai J, et al. Among authors: skosyrski s. EMBO Mol Med. 2012 Sep;4(9):980-91. doi: 10.1002/emmm.201101084. Epub 2012 Aug 20. EMBO Mol Med. 2012. PMID: 22903875 Free PMC article.
Lack of netrin-4 modulates pathologic neovascularization in the eye.
Kociok N, Crespo-Garcia S, Liang Y, Klein SV, Nürnberg C, Reichhart N, Skosyrski S, Moritz E, Maier AK, Brunken WJ, Strauß O, Koch M, Joussen AM. Kociok N, et al. Among authors: skosyrski s. Sci Rep. 2016 Jan 6;6:18828. doi: 10.1038/srep18828. Sci Rep. 2016. PMID: 26732856 Free PMC article.
Hypertensive retinopathy in a transgenic angiotensin-based model.
Reichhart N, Haase N, Crespo-Garcia S, Skosyrski S, Herrspiegel C, Kociok N, Fuchshofer R, Dillinger A, Poglitsch M, Müller DN, Joussen AM, Luft FC, Dechend R, Strauß O. Reichhart N, et al. Among authors: skosyrski s. Clin Sci (Lond). 2016 Jul 1;130(13):1075-88. doi: 10.1042/CS20160092. Epub 2016 Mar 29. Clin Sci (Lond). 2016. PMID: 27026533
Lack of netrin-4 alters vascular remodeling in the retina.
Crespo-Garcia S, Reichhart N, Wigdahl J, Skosyrski S, Kociok N, Strauß O, Joussen AM. Crespo-Garcia S, et al. Among authors: skosyrski s. Graefes Arch Clin Exp Ophthalmol. 2019 Oct;257(10):2179-2184. doi: 10.1007/s00417-019-04447-3. Epub 2019 Aug 26. Graefes Arch Clin Exp Ophthalmol. 2019. PMID: 31451908
21 results