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234 results

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Page 1
Radiosynthesis and biodistribution of a histamine H3 receptor antagonist 4-[3-(4-piperidin-1-yl-but-1-ynyl)-[11C]benzyl]-morpholine: evaluation of a potential PET ligand.
Airaksinen AJ, Jablonowski JA, van der Mey M, Barbier AJ, Klok RP, Verbeek J, Schuit R, Herscheid JD, Leysen JE, Carruthers NI, Lammertsma AA, Windhorst AD. Airaksinen AJ, et al. Among authors: leysen je. Nucl Med Biol. 2006 Aug;33(6):801-10. doi: 10.1016/j.nucmedbio.2006.05.008. Nucl Med Biol. 2006. PMID: 16934699
First evaluation of [11C]R116301 as an in vivo tracer of NK1 receptors in man.
Wolfensberger SP, van Berckel BN, Airaksinen AJ, Maruyama K, Lubberink M, Boellaard R, Carey WD, Reddingius W, Veltman DJ, Windhorst AD, Leysen JE, Lammertsma AA. Wolfensberger SP, et al. Among authors: leysen je. Mol Imaging Biol. 2009 Jul-Aug;11(4):241-5. doi: 10.1007/s11307-009-0204-5. Epub 2009 Mar 31. Mol Imaging Biol. 2009. PMID: 19333655 Free PMC article.
Quantification of the neurokinin 1 receptor ligand [¹¹C]R116301.
Wolfensberger SP, Maruyama K, van Berckel BN, Lubberink M, Airaksinen AJ, Boellaard R, Luurtsema G, Reddingius W, Janssens FE, Veltman DJ, Windhorst AD, Leysen JE, Lammertsma AA. Wolfensberger SP, et al. Among authors: leysen je. Nucl Med Commun. 2011 Oct;32(10):896-902. doi: 10.1097/MNM.0b013e328347e96f. Nucl Med Commun. 2011. PMID: 21876400 Clinical Trial.
Synthesis and preclinical evaluation of carbon-11 labelled N-((5-(4-fluoro-2-[(11)C]methoxyphenyl)pyridin-3-yl)methyl)cyclopentanamine as a PET tracer for NR2B subunit-containing NMDA receptors.
Christiaans JA, Klein PJ, Metaxas A, Kooijman EJ, Schuit RC, Leysen JE, Lammertsma AA, van Berckel BN, Windhorst AD. Christiaans JA, et al. Among authors: leysen je. Nucl Med Biol. 2014 Sep;41(8):670-80. doi: 10.1016/j.nucmedbio.2014.04.131. Epub 2014 May 10. Nucl Med Biol. 2014. PMID: 24929961
The dopamine stabilizer (-)-OSU6162 occupies a subpopulation of striatal dopamine D2/D3 receptors: an [(11)C]raclopride PET study in healthy human subjects.
Tolboom N, Berendse HW, Leysen JE, Yaqub M, van Berckel BN, Schuit RC, Ponsen MM, Bakker E, Hoetjes NJ, Windhorst AD, Carlsson ML, Lammertsma AA, Carlsson A. Tolboom N, et al. Among authors: leysen je. Neuropsychopharmacology. 2015 Jan;40(2):472-9. doi: 10.1038/npp.2014.195. Epub 2014 Aug 5. Neuropsychopharmacology. 2015. PMID: 25248987 Free PMC article.
Preclinical evaluation of [(18)F]PK-209, a new PET ligand for imaging the ion-channel site of NMDA receptors.
Golla SS, Klein PJ, Bakker J, Schuit RC, Christiaans JA, van Geest L, Kooijman EJ, Oropeza-Seguias GM, Langermans JA, Leysen JE, Boellaard R, Windhorst AD, van Berckel BN, Metaxas A. Golla SS, et al. Among authors: leysen je. Nucl Med Biol. 2015 Feb;42(2):205-12. doi: 10.1016/j.nucmedbio.2014.09.006. Epub 2014 Sep 30. Nucl Med Biol. 2015. PMID: 25451213
234 results