Hoque R - Search Results

1

A novel small-molecule enantiomeric analogue of traditional (-)-morphinans has specific TLR9 antagonist properties and reduces sterile inflammation-induced organ damage.

Hoque R, Farooq A, Malik A, Trawick BN, Berberich DW, McClurg JP, Galen KP, Mehal W. Hoque R, et al. J Immunol. 2013 Apr 15;190(8):4297-304. doi: 10.4049/jimmunol.1202184. Epub 2013 Mar 15. J Immunol. 2013. PMID: 23509352 Free PMC article.

2

Sterile inflammatory response in acute pancreatitis.

Hoque R, Malik AF, Gorelick F, Mehal WZ. Hoque R, et al. Pancreas. 2012 Apr;41(3):353-7. doi: 10.1097/MPA.0b013e3182321500. Pancreas. 2012. PMID: 22415665 Free PMC article. Review.

3

Sterile inflammation in the liver and pancreas.

Hoque R, Farooq A, Mehal WZ. Hoque R, et al. J Gastroenterol Hepatol. 2013 Aug;28 Suppl 1(0 1):61-7. doi: 10.1111/jgh.12018. J Gastroenterol Hepatol. 2013. PMID: 23855298 Free PMC article. Review.

4

TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis.

Hoque R, Sohail M, Malik A, Sarwar S, Luo Y, Shah A, Barrat F, Flavell R, Gorelick F, Husain S, Mehal W. Hoque R, et al. Gastroenterology. 2011 Jul;141(1):358-69. doi: 10.1053/j.gastro.2011.03.041. Epub 2011 Mar 24. Gastroenterology. 2011. PMID: 21439959 Free PMC article.

5

P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice.

Hoque R, Sohail MA, Salhanick S, Malik AF, Ghani A, Robson SC, Mehal WZ. Hoque R, et al. Am J Physiol Gastrointest Liver Physiol. 2012 May 15;302(10):G1171-9. doi: 10.1152/ajpgi.00352.2011. Epub 2012 Mar 1. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22383490 Free PMC article.

6

Therapeutic strategies in inflammasome mediated diseases of the liver.

Hoque R, Vodovotz Y, Mehal W. Hoque R, et al. J Hepatol. 2013 May;58(5):1047-52. doi: 10.1016/j.jhep.2012.12.017. Epub 2012 Dec 21. J Hepatol. 2013. PMID: 23266490 Free PMC article.

7

Lactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunity.

Hoque R, Farooq A, Ghani A, Gorelick F, Mehal WZ. Hoque R, et al. Gastroenterology. 2014 Jun;146(7):1763-74. doi: 10.1053/j.gastro.2014.03.014. Epub 2014 Mar 20. Gastroenterology. 2014. PMID: 24657625 Free PMC article.

8

Activation of N-methyl-d-aspartate receptor downregulates inflammasome activity and liver inflammation via a β-arrestin-2 pathway.

Farooq A, Hoque R, Ouyang X, Farooq A, Ghani A, Ahsan K, Guerra M, Mehal WZ. Farooq A, et al. Among authors: hoque r. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1;307(7):G732-40. doi: 10.1152/ajpgi.00073.2014. Epub 2014 Aug 7. Am J Physiol Gastrointest Liver Physiol. 2014. PMID: 25104498 Free PMC article.

9

Inflammasomes in pancreatic physiology and disease.

Hoque R, Mehal WZ. Hoque R, et al. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15;308(8):G643-51. doi: 10.1152/ajpgi.00388.2014. Epub 2015 Feb 19. Am J Physiol Gastrointest Liver Physiol. 2015. PMID: 25700081 Free PMC article. Review.

10

Inflammasome components Asc and caspase-1 mediate biomaterial-induced inflammation and foreign body response.

Malik AF, Hoque R, Ouyang X, Ghani A, Hong E, Khan K, Moore LB, Ng G, Munro F, Flavell RA, Shi Y, Kyriakides TR, Mehal WZ. Malik AF, et al. Among authors: hoque r. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20095-100. doi: 10.1073/pnas.1105152108. Epub 2011 Nov 22. Proc Natl Acad Sci U S A. 2011. PMID: 22109549 Free PMC article.

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