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2,485 results

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A genome-wide RNAi screen identifies proteins modulating aberrant FLT3-ITD signaling.
Caldarelli A, Müller JP, Paskowski-Rogacz M, Herrmann K, Bauer R, Koch S, Heninger AK, Krastev D, Ding L, Kasper S, Fischer T, Brodhun M, Böhmer FD, Buchholz F. Caldarelli A, et al. Among authors: bauer r. Leukemia. 2013 Dec;27(12):2301-10. doi: 10.1038/leu.2013.83. Epub 2013 Mar 19. Leukemia. 2013. PMID: 23508117 Free PMC article.
Anchoring of FLT3 in the endoplasmic reticulum alters signaling quality.
Schmidt-Arras D, Böhmer SA, Koch S, Müller JP, Blei L, Cornils H, Bauer R, Korasikha S, Thiede C, Böhmer FD. Schmidt-Arras D, et al. Among authors: bauer r. Blood. 2009 Apr 9;113(15):3568-76. doi: 10.1182/blood-2007-10-121426. Epub 2009 Feb 9. Blood. 2009. PMID: 19204327 Free article.
NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells.
Jayavelu AK, Müller JP, Bauer R, Böhmer SA, Lässig J, Cerny-Reiterer S, Sperr WR, Valent P, Maurer B, Moriggl R, Schröder K, Shah AM, Fischer M, Scholl S, Barth J, Oellerich T, Berg T, Serve H, Frey S, Fischer T, Heidel FH, Böhmer FD. Jayavelu AK, et al. Among authors: bauer r. Leukemia. 2016 Feb;30(2):473-83. doi: 10.1038/leu.2015.234. Epub 2015 Aug 26. Leukemia. 2016. PMID: 26308771
Protein-tyrosine phosphatase DEP-1 controls receptor tyrosine kinase FLT3 signaling.
Arora D, Stopp S, Böhmer SA, Schons J, Godfrey R, Masson K, Razumovskaya E, Rönnstrand L, Tänzer S, Bauer R, Böhmer FD, Müller JP. Arora D, et al. Among authors: bauer r. J Biol Chem. 2011 Apr 1;286(13):10918-29. doi: 10.1074/jbc.M110.205021. Epub 2011 Jan 24. J Biol Chem. 2011. PMID: 21262971 Free PMC article.
Cell transformation by FLT3 ITD in acute myeloid leukemia involves oxidative inactivation of the tumor suppressor protein-tyrosine phosphatase DEP-1/ PTPRJ.
Godfrey R, Arora D, Bauer R, Stopp S, Müller JP, Heinrich T, Böhmer SA, Dagnell M, Schnetzke U, Scholl S, Östman A, Böhmer FD. Godfrey R, et al. Among authors: bauer r. Blood. 2012 May 10;119(19):4499-511. doi: 10.1182/blood-2011-02-336446. Epub 2012 Mar 20. Blood. 2012. PMID: 22438257 Free article.
SHP1 regulates a STAT6-ITGB3 axis in FLT3ITD-positive AML cells.
Reich D, Kresinsky A, Müller JP, Bauer R, Kallenbach J, Schnoeder TM, Heidel FH, Fässler R, Mann M, Böhmer FD, Jayavelu AK. Reich D, et al. Among authors: bauer r. Leukemia. 2020 May;34(5):1444-1449. doi: 10.1038/s41375-019-0676-5. Epub 2019 Dec 13. Leukemia. 2020. PMID: 31836852 No abstract available.
2,485 results