Maneval DC - Search Results

1

Phase I trial of intravesical recombinant adenovirus mediated interferon-α2b formulated in Syn3 for Bacillus Calmette-Guérin failures in nonmuscle invasive bladder cancer.

Dinney CP, Fisher MB, Navai N, O'Donnell MA, Cutler D, Abraham A, Young S, Hutchins B, Caceres M, Kishnani N, Sode G, Cullen C, Zhang G, Grossman HB, Kamat AM, Gonzales M, Kincaid M, Ainslie N, Maneval DC, Wszolek MF, Benedict WF. Dinney CP, et al. Among authors: maneval dc. J Urol. 2013 Sep;190(3):850-6. doi: 10.1016/j.juro.2013.03.030. Epub 2013 Mar 15. J Urol. 2013. PMID: 23507396 Free PMC article. Clinical Trial.

2

Syn3 provides high levels of intravesical adenoviral-mediated gene transfer for gene therapy of genetically altered urothelium and superficial bladder cancer.

Yamashita M, Rosser CJ, Zhou JH, Zhang XQ, Connor RJ, Engler H, Maneval DC, Karashima T, Czerniak BA, Dinney CP, Benedict WF. Yamashita M, et al. Among authors: maneval dc. Cancer Gene Ther. 2002 Aug;9(8):687-91. doi: 10.1038/sj.cgt.7700488. Cancer Gene Ther. 2002. PMID: 12136430

3

Intravesical Ad-IFNalpha causes marked regression of human bladder cancer growing orthotopically in nude mice and overcomes resistance to IFN-alpha protein.

Benedict WF, Tao Z, Kim CS, Zhang X, Zhou JH, Adam L, McConkey DJ, Papageorgiou A, Munsell M, Philopena J, Engler H, Demers W, Maneval DC, Dinney CP, Connor RJ. Benedict WF, et al. Among authors: maneval dc. Mol Ther. 2004 Sep;10(3):525-32. doi: 10.1016/j.ymthe.2004.05.027. Mol Ther. 2004. PMID: 15336652 Free article.

4

Toxicity and exposure of an adenovirus containing human interferon alpha-2b following intracystic administration in cynomolgus monkeys.

Veneziale RW, Kishnani NS, Nelson J, Resendez JC, Frank DW, Cai XY, Xie L, Cullen C, Frugone CA, Rosenfeld C, Hubbell J, Maxwell SE, Sugarman BJ, Hutchins B, Maneval D, Treinen KA. Veneziale RW, et al. Gene Ther. 2012 Jul;19(7):742-51. doi: 10.1038/gt.2011.116. Epub 2011 Sep 8. Gene Ther. 2012. PMID: 21900961

5

Enhancement of intravesical delivery with Syn3 potentiates interferon-alpha2b gene therapy for superficial bladder cancer.

Nagabhushan TL, Maneval DC, Benedict WF, Wen SF, Ihnat PM, Engler H, Connor RJ. Nagabhushan TL, et al. Among authors: maneval dc. Cytokine Growth Factor Rev. 2007 Oct-Dec;18(5-6):389-94. doi: 10.1016/j.cytogfr.2007.06.007. Epub 2007 Aug 9. Cytokine Growth Factor Rev. 2007. PMID: 17692556 Review.

6

Successful adenovirus-mediated wild-type p53 gene transfer in patients with bladder cancer by intravesical vector instillation.

Kuball J, Wen SF, Leissner J, Atkins D, Meinhardt P, Quijano E, Engler H, Hutchins B, Maneval DC, Grace MJ, Fritz MA, Störkel S, Thüroff JW, Huber C, Schuler M. Kuball J, et al. Among authors: maneval dc. J Clin Oncol. 2002 Feb 15;20(4):957-65. doi: 10.1200/JCO.2002.20.4.957. J Clin Oncol. 2002. PMID: 11844817 Clinical Trial.

7

Sustained intravesical interferon protein exposure is achieved using an adenoviral-mediated gene delivery system: a study in rats evaluating dosing regimens.

Connor RJ, Anderson JM, Machemer T, Maneval DC, Engler H. Connor RJ, et al. Among authors: maneval dc. Urology. 2005 Jul;66(1):224-9. doi: 10.1016/j.urology.2005.02.015. Urology. 2005. PMID: 15992886

8

Assessment of p53 gene transfer and biological activities in a clinical study of adenovirus-p53 gene therapy for recurrent ovarian cancer.

Wen SF, Mahavni V, Quijano E, Shinoda J, Grace M, Musco-Hobkinson ML, Yang TY, Chen Y, Runnenbaum I, Horowitz J, Maneval D, Hutchins B, Buller R. Wen SF, et al. Cancer Gene Ther. 2003 Mar;10(3):224-38. doi: 10.1038/sj.cgt.7700562. Cancer Gene Ther. 2003. PMID: 12637944 Clinical Trial.

9

SCH 412499: biodistribution and safety of an adenovirus containing P21(WAF-1/CIP-1) following subconjunctival injection in Cynomolgus monkeys.

Veneziale RW, Bral CM, Sinha DP, Watkins RW, Cartwright ME, Rosenblum IY, Treinen KA, Kishnani NS, Nelson J, Chen Z, Faha B, Maneval D, Munger RJ, Cai XY, Cullen C, Arezzo JC. Veneziale RW, et al. Cutan Ocul Toxicol. 2007;26(2):83-105. doi: 10.1080/15569520701212167. Cutan Ocul Toxicol. 2007. PMID: 17612977

10

Ethanol improves adenovirus-mediated gene transfer and expression to the bladder epithelium of rodents.

Engler H, Anderson SC, Machemer TR, Philopena JM, Connor RJ, Wen SF, Maneval DC. Engler H, et al. Among authors: maneval dc. Urology. 1999 May;53(5):1049-53. doi: 10.1016/s0090-4295(98)00641-4. Urology. 1999. PMID: 10223504

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