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677 results

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Page 1
Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.
Alonzi DS, Kukushkin NV, Allman SA, Hakki Z, Williams SJ, Pierce L, Dwek RA, Butters TD. Alonzi DS, et al. Among authors: williams sj. Cell Mol Life Sci. 2013 Aug;70(15):2799-814. doi: 10.1007/s00018-013-1304-6. Epub 2013 Mar 16. Cell Mol Life Sci. 2013. PMID: 23503623 Free PMC article.
Structure of human endo-α-1,2-mannosidase (MANEA), an antiviral host-glycosylation target.
Sobala ŁF, Fernandes PZ, Hakki Z, Thompson AJ, Howe JD, Hill M, Zitzmann N, Davies S, Stamataki Z, Butters TD, Alonzi DS, Williams SJ, Davies GJ. Sobala ŁF, et al. Among authors: williams sj. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29595-29601. doi: 10.1073/pnas.2013620117. Epub 2020 Nov 5. Proc Natl Acad Sci U S A. 2020. PMID: 33154157 Free PMC article.
Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase.
Thompson AJ, Williams RJ, Hakki Z, Alonzi DS, Wennekes T, Gloster TM, Songsrirote K, Thomas-Oates JE, Wrodnigg TM, Spreitz J, Stütz AE, Butters TD, Williams SJ, Davies GJ. Thompson AJ, et al. Among authors: williams sj, williams rj. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):781-6. doi: 10.1073/pnas.1111482109. Epub 2012 Jan 4. Proc Natl Acad Sci U S A. 2012. PMID: 22219371 Free PMC article.
Spiro-epoxyglycosides as Activity-Based Probes for Glycoside Hydrolase Family 99 Endomannosidase/Endomannanase.
Schröder SP, Kallemeijn WW, Debets MF, Hansen T, Sobala LF, Hakki Z, Williams SJ, Beenakker TJM, Aerts JMFG, van der Marel GA, Codée JDC, Davies GJ, Overkleeft HS. Schröder SP, et al. Among authors: williams sj. Chemistry. 2018 Jul 11;24(39):9983-9992. doi: 10.1002/chem.201801902. Epub 2018 Jun 21. Chemistry. 2018. PMID: 29797675 Free PMC article.
Evidence for a boat conformation at the transition state of GH76 α-1,6-mannanases--key enzymes in bacterial and fungal mannoprotein metabolism.
Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Thompson AJ, et al. Among authors: williams sj. Angew Chem Int Ed Engl. 2015 Apr 27;54(18):5378-82. doi: 10.1002/anie.201410502. Epub 2015 Mar 13. Angew Chem Int Ed Engl. 2015. PMID: 25772148
Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism.
Cuskin F, Lowe EC, Temple MJ, Zhu Y, Cameron E, Pudlo NA, Porter NT, Urs K, Thompson AJ, Cartmell A, Rogowski A, Hamilton BS, Chen R, Tolbert TJ, Piens K, Bracke D, Vervecken W, Hakki Z, Speciale G, Munōz-Munōz JL, Day A, Peña MJ, McLean R, Suits MD, Boraston AB, Atherly T, Ziemer CJ, Williams SJ, Davies GJ, Abbott DW, Martens EC, Gilbert HJ. Cuskin F, et al. Among authors: williams sj. Nature. 2015 Jan 8;517(7533):165-169. doi: 10.1038/nature13995. Nature. 2015. PMID: 25567280 Free PMC article.
An Epoxide Intermediate in Glycosidase Catalysis.
Sobala LF, Speciale G, Zhu S, Raich L, Sannikova N, Thompson AJ, Hakki Z, Lu D, Shamsi Kazem Abadi S, Lewis AR, Rojas-Cervellera V, Bernardo-Seisdedos G, Zhang Y, Millet O, Jiménez-Barbero J, Bennet AJ, Sollogoub M, Rovira C, Davies GJ, Williams SJ. Sobala LF, et al. Among authors: williams sj. ACS Cent Sci. 2020 May 27;6(5):760-770. doi: 10.1021/acscentsci.0c00111. Epub 2020 Apr 16. ACS Cent Sci. 2020. PMID: 32490192 Free PMC article.
Corrigendum: Evidence for a Boat Conformation at the Transition State of GH76 α-1,6-Mannanases--Key Enzymes in Bacterial and Fungal Mannoprotein Metabolism.
Thompson AJ, Speciale G, Iglesias-Fernández J, Hakki Z, Belz T, Cartmell A, Spears RJ, Chandler E, Temple MJ, Stepper J, Gilbert HJ, Rovira C, Williams SJ, Davies GJ. Thompson AJ, et al. Among authors: williams sj. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):1949. doi: 10.1002/anie.201511540. Angew Chem Int Ed Engl. 2016. PMID: 26836331 No abstract available.
677 results