Alonzi DS - Search Results

1

Glycoprotein misfolding in the endoplasmic reticulum: identification of released oligosaccharides reveals a second ER-associated degradation pathway for Golgi-retrieved proteins.

Alonzi DS, Kukushkin NV, Allman SA, Hakki Z, Williams SJ, Pierce L, Dwek RA, Butters TD. Alonzi DS, et al. Cell Mol Life Sci. 2013 Aug;70(15):2799-814. doi: 10.1007/s00018-013-1304-6. Epub 2013 Mar 16. Cell Mol Life Sci. 2013. PMID: 23503623 Free PMC article.

2

Glucosylated free oligosaccharides are biomarkers of endoplasmic- reticulum alpha-glucosidase inhibition.

Alonzi DS, Neville DC, Lachmann RH, Dwek RA, Butters TD. Alonzi DS, et al. Biochem J. 2008 Jan 15;409(2):571-80. doi: 10.1042/BJ20070748. Biochem J. 2008. PMID: 17868040

3

Carbasugar-thioether pseudodisaccharides related to N-glycan biosynthesis.

Cumpstey I, Alonzi DS, Butters TD. Cumpstey I, et al. Among authors: alonzi ds. Carbohydr Res. 2009 Mar 10;344(4):454-9. doi: 10.1016/j.carres.2008.12.023. Epub 2009 Jan 3. Carbohydr Res. 2009. PMID: 19166995

4

Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells.

Butters TD, Alonzi DS, Kukushkin NV, Ren Y, Blériot Y. Butters TD, et al. Among authors: alonzi ds. Glycoconj J. 2009 Dec;26(9):1109-16. doi: 10.1007/s10719-009-9231-3. Glycoconj J. 2009. PMID: 19234785

5

Synthesis and biological characterisation of novel N-alkyl-deoxynojirimycin alpha-glucosidase inhibitors.

Rawlings AJ, Lomas H, Pilling AW, Lee MJ, Alonzi DS, Rountree JS, Jenkinson SF, Fleet GW, Dwek RA, Jones JH, Butters TD. Rawlings AJ, et al. Among authors: alonzi ds. Chembiochem. 2009 Apr 17;10(6):1101-5. doi: 10.1002/cbic.200900025. Chembiochem. 2009. PMID: 19294724

6

Towards a stable noeuromycin analog with a D-manno configuration: synthesis and glycosidase inhibition of D-manno-like tri- and tetrahydroxylated azepanes.

Deschamp J, Mondon M, Nakagawa S, Kato A, Alonzi DS, Butters TD, Zhang Y, Sollogoub M, Blériot Y. Deschamp J, et al. Among authors: alonzi ds. Bioorg Med Chem. 2012 Jan 15;20(2):641-9. doi: 10.1016/j.bmc.2010.09.053. Epub 2010 Oct 1. Bioorg Med Chem. 2012. PMID: 20971647

7

Combination of α-glucosidase inhibitor and ribavirin for the treatment of dengue virus infection in vitro and in vivo.

Chang J, Schul W, Butters TD, Yip A, Liu B, Goh A, Lakshminarayana SB, Alonzi D, Reinkensmeier G, Pan X, Qu X, Weidner JM, Wang L, Yu W, Borune N, Kinch MA, Rayahin JE, Moriarty R, Xu X, Shi PY, Guo JT, Block TM. Chang J, et al. Antiviral Res. 2011 Jan;89(1):26-34. doi: 10.1016/j.antiviral.2010.11.002. Epub 2010 Nov 10. Antiviral Res. 2011. PMID: 21073903 Free PMC article.

8

4-C-Me-DAB and 4-C-Me-LAB - enantiomeric alkyl-branched pyrrolidine iminosugars - are specific and potent α-glucosidase inhibitors; acetone as the sole protecting group.

da Cruz FP, Newberry S, Jenkinson SF, Wormald MR, Butters TD, Alonzi DS, Nakagawa S, Becq F, Norez C, Nash RJ, Kato A, Fleet GW. da Cruz FP, et al. Among authors: alonzi ds. Tetrahedron Lett. 2011 Jan 12;52(2):219-223. doi: 10.1016/j.tetlet.2010.10.173. Tetrahedron Lett. 2011. PMID: 21157573 Free PMC article.

9

Inhibitors of endoplasmic reticulum alpha-glucosidases potently suppress hepatitis C virus virion assembly and release.

Qu X, Pan X, Weidner J, Yu W, Alonzi D, Xu X, Butters T, Block T, Guo JT, Chang J. Qu X, et al. Antimicrob Agents Chemother. 2011 Mar;55(3):1036-44. doi: 10.1128/AAC.01319-10. Epub 2010 Dec 20. Antimicrob Agents Chemother. 2011. PMID: 21173177 Free PMC article.

10

Urinary glycan markers for disease.

Alonzi DS, Su YH, Butters TD. Alonzi DS, et al. Biochem Soc Trans. 2011 Jan;39(1):393-8. doi: 10.1042/BST0390393. Biochem Soc Trans. 2011. PMID: 21265811 Review.

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