Gomeni R - Search Results

1

Model-based approaches to increase efficiency of drug development in schizophrenia: a can't miss opportunity.

Nucci G, Gomeni R, Poggesi I. Nucci G, et al. Among authors: gomeni r. Expert Opin Drug Discov. 2009 Aug;4(8):837-56. doi: 10.1517/17460440903036073. Epub 2009 Jun 24. Expert Opin Drug Discov. 2009. PMID: 23496270

2

Bayesian population approaches to the analysis of dose escalation studies.

Russu A, De Nicolao G, Poggesi I, Neve M, Gomeni R. Russu A, et al. Among authors: gomeni r. Comput Methods Programs Biomed. 2012 Aug;107(2):189-201. doi: 10.1016/j.cmpb.2011.05.010. Epub 2011 Jul 20. Comput Methods Programs Biomed. 2012. PMID: 21764475

3

Bayesian population modeling of phase I dose escalation studies: Gaussian process versus parametric approaches.

Russu A, Poggesi I, Gomeni R, De Nicolao G. Russu A, et al. Among authors: gomeni r. IEEE Trans Biomed Eng. 2011 Nov;58(11):3156-64. doi: 10.1109/TBME.2011.2164614. Epub 2011 Aug 15. IEEE Trans Biomed Eng. 2011. PMID: 21846598

4

Pharmacokinetics and time-course of D(2) receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients.

Catafau AM, Penengo MM, Nucci G, Bullich S, Corripio I, Parellada E, García-Ribera C, Gomeni R, Merlo-Pich E; Barcelona Clinical Imaging in Psychiatry Group. Catafau AM, et al. Among authors: gomeni r. J Psychopharmacol. 2008 Nov;22(8):882-94. doi: 10.1177/0269881107083810. Epub 2008 Feb 28. J Psychopharmacol. 2008. PMID: 18308793

5

Joint modeling of efficacy, dropout, and tolerability in flexible-dose trials: a case study in depression.

Russu A, Marostica E, De Nicolao G, Hooker AC, Poggesi I, Gomeni R, Zamuner S. Russu A, et al. Among authors: gomeni r. Clin Pharmacol Ther. 2012 May;91(5):863-71. doi: 10.1038/clpt.2011.322. Clin Pharmacol Ther. 2012. PMID: 22472989 Clinical Trial.

6

Phase I studies on the safety, tolerability, pharmacokinetics and pharmacodynamics of SB-649868, a novel dual orexin receptor antagonist.

Bettica P, Nucci G, Pyke C, Squassante L, Zamuner S, Ratti E, Gomeni R, Alexander R. Bettica P, et al. Among authors: gomeni r. J Psychopharmacol. 2012 Aug;26(8):1058-70. doi: 10.1177/0269881111408954. Epub 2011 Jul 5. J Psychopharmacol. 2012. PMID: 21730017 Clinical Trial.

7

Multiple dose pharmacokinetics of paroxetine in children and adolescents with major depressive disorder or obsessive-compulsive disorder.

Findling RL, Nucci G, Piergies AA, Gomeni R, Bartolic EI, Fong R, Carpenter DJ, Leeder JS, Gaedigk A, Danoff TM. Findling RL, et al. Among authors: gomeni r. Neuropsychopharmacology. 2006 Jun;31(6):1274-85. doi: 10.1038/sj.npp.1300960. Neuropsychopharmacology. 2006. PMID: 16319918 Clinical Trial.

8

Model-based approach and signal detection theory to evaluate the performance of recruitment centers in clinical trials with antidepressant drugs.

Merlo-Pich E, Gomeni R. Merlo-Pich E, et al. Among authors: gomeni r. Clin Pharmacol Ther. 2008 Sep;84(3):378-84. doi: 10.1038/clpt.2008.70. Epub 2008 Apr 30. Clin Pharmacol Ther. 2008. PMID: 18449185

9

Bayesian modelling and ROC analysis to predict placebo responders using clinical score measured in the initial weeks of treatment in depression trials.

Gomeni R, Merlo-Pich E. Gomeni R, et al. Br J Clin Pharmacol. 2007 May;63(5):595-613. doi: 10.1111/j.1365-2125.2006.02815.x. Br J Clin Pharmacol. 2007. PMID: 17488364 Free PMC article.

10

A new population-enrichment strategy to improve efficiency of placebo-controlled clinical trials of antidepressant drugs.

Merlo-Pich E, Alexander RC, Fava M, Gomeni R. Merlo-Pich E, et al. Among authors: gomeni r. Clin Pharmacol Ther. 2010 Nov;88(5):634-42. doi: 10.1038/clpt.2010.159. Epub 2010 Sep 22. Clin Pharmacol Ther. 2010. PMID: 20861834

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