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Gout-causing Q141K mutation in ABCG2 leads to instability of the nucleotide-binding domain and can be corrected with small molecules.
Woodward OM, Tukaye DN, Cui J, Greenwell P, Constantoulakis LM, Parker BS, Rao A, Köttgen M, Maloney PC, Guggino WB. Woodward OM, et al. Among authors: guggino wb. Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5223-8. doi: 10.1073/pnas.1214530110. Epub 2013 Mar 14. Proc Natl Acad Sci U S A. 2013. PMID: 23493553 Free PMC article.
Immunocytochemical localization of the cystic fibrosis gene product CFTR.
Crawford I, Maloney PC, Zeitlin PL, Guggino WB, Hyde SC, Turley H, Gatter KC, Harris A, Higgins CF. Crawford I, et al. Among authors: guggino wb. Proc Natl Acad Sci U S A. 1991 Oct 15;88(20):9262-6. doi: 10.1073/pnas.88.20.9262. Proc Natl Acad Sci U S A. 1991. PMID: 1718002 Free PMC article.
Sensitivity of a renal K+ channel (ROMK2) to the inhibitory sulfonylurea compound glibenclamide is enhanced by coexpression with the ATP-binding cassette transporter cystic fibrosis transmembrane regulator.
McNicholas CM, Guggino WB, Schwiebert EM, Hebert SC, Giebisch G, Egan ME. McNicholas CM, et al. Among authors: guggino wb. Proc Natl Acad Sci U S A. 1996 Jul 23;93(15):8083-8. doi: 10.1073/pnas.93.15.8083. Proc Natl Acad Sci U S A. 1996. PMID: 8755607 Free PMC article.
268 results